Structured evidence table for Glucosamine Joint Function Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Glucosamine Joint Function Randomized Trial | This umbrella review synthesized evidence from published systematic reviews and meta-analyses on the effectiveness and safety of glucosamine in knee OA. | 3 | Li Y (2026) | Glucosamine for knee osteoarthritis: an umbrella review. |
| Glucosamine Joint Function Randomized Trial | Glucosamine was associated with significant slowing of JSN progression (SMD - 0.32, p = 0.01), though this signal derived mainly from long-duration sulfate trials. | 3 | Li Y (2026) | Glucosamine for knee osteoarthritis: an umbrella review. |
| Glucosamine Joint Function Randomized Trial | Conclusion Glucosamine demonstrated at most minimal-to-modest efficacy for knee OA, yielding a small pain reduction and possible slowing of radiographic progression but no clear functional benefit, with effects at or below the threshold of clinical importance. | 3 | Li Y (2026) | Glucosamine for knee osteoarthritis: an umbrella review. |
| Glucosamine Joint Function Randomized Trial | Background Knee osteoarthritis (OA) is a common cause of pain and disability without a cure. | 3 | Li Y (2026) | Glucosamine for knee osteoarthritis: an umbrella review. |
| Glucosamine Joint Function Randomized Trial | Background Osteoporosis (OP) associated with knee osteoarthritis (KOA) is common in older men and postmenopausal women, and it is important to find reliable and effective treatments for this disease to improve joint function and bone metabolism in this population. | 4 | Yang JJ (2022) | Clinical Efficacy of Glucosamine plus Sodium Hyaluronate for Osteoporosis Complicated by Knee Osteoarthritis and Its Influence on Joint Function and Bone Metabolic Markers. |
| Glucosamine Joint Function Randomized Trial | Objective To clarify the clinical efficacy of glucosamine (GlcN) plus sodium hyaluronate (SH) for OP complicated by KOA (OP + KOA) and its influence on joint function and bone metabolic markers (BMMs). | 4 | Yang JJ (2022) | Clinical Efficacy of Glucosamine plus Sodium Hyaluronate for Osteoporosis Complicated by Knee Osteoarthritis and Its Influence on Joint Function and Bone Metabolic Markers. |
Source documents