topicGinkgo Sleep Quality Randomized Trial
claimConclusion Current RCT evidence shows inconsistent and limited findings, and no firm conclusions can be drawn about whether any OTC therapy provides symptomatic benefit.
evidence level1
citationMenon R (2026)
sourceEffectiveness of Over-The-Counter Treatments for Tinnitus Symptom Relief: A Systematic Review.
topicGinkgo Sleep Quality Randomized Trial
claimLevel of evidence 1 (Systematic review of RCTs with low-moderate heterogeneity).
evidence level1
citationMenon R (2026)
sourceEffectiveness of Over-The-Counter Treatments for Tinnitus Symptom Relief: A Systematic Review.
topicGinkgo Sleep Quality Randomized Trial
claimObjective To review the effectiveness of over-the-counter (OTC) treatments in reducing tinnitus symptom severity as measured by the Tinnitus Handicap Inventory (THI) in randomized controlled trials.
evidence level1
citationMenon R (2026)
sourceEffectiveness of Over-The-Counter Treatments for Tinnitus Symptom Relief: A Systematic Review.
topicGinkgo Sleep Quality Randomized Trial
claimMethods A comprehensive search was conducted in PubMed, Embase, Cochrane CENTRAL, ClinicalTrials.gov, and WHO ICTRP through March 2025.
evidence level1
citationMenon R (2026)
sourceEffectiveness of Over-The-Counter Treatments for Tinnitus Symptom Relief: A Systematic Review.
topicGinkgo Sleep Quality Randomized Trial
claimThese limitations have catalyzed an increased global focus on nutraceuticals and phytomedicines possessing multimodal biological activities that transcend mere monoamine reuptake inhibition.
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicGinkgo Sleep Quality Randomized Trial
claimUnlike prior reviews that focus on individual herbs or broadly defined adaptogens, the present review integrates mechanistic, preclinical, and clinical evidence across these three agents to highlight their complementary rather than redundant actions.
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicGinkgo Sleep Quality Randomized Trial
claimRhodiola rosea Ginkgo biloba Withania somnifera A comprehensive and structured literature search was conducted to identify preclinical, translational, and clinical evidence related to the antidepressant effects and underlying neurobiological mechanisms of,, and(Ashwagandha).
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders
topicGinkgo Sleep Quality Randomized Trial
claim1 2 3 Rhodiola rosea Ginkgo biloba Withania somnifera Depression constitutes one of the most incapacitating neuropsychiatric disorders globally ().
evidence level3
citationLi Xikun (2026)
sourceRhodiola rosea , Ginkgo biloba , and Ashwagandha as novel antidepressant supplements: converging monoaminergic, neurotrophic, anti-inflammatory, and brain health pathways in depressive disorders