topicGinkgo Cognition Meta-Analysis
claimSignificant treatment effects of 240 mg EGb 761 daily versus placebo were found for cognition ( p = 0.0467), activities of daily living ( p = 0.0230), and global clinical impression ( p = 0.0371).
evidence level1
citationFeng JX (2026)
source<i>Ginkgo biloba</i> extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials.
topicGinkgo Cognition Meta-Analysis
claimConclusion The results of our meta-analysis of patients with mild to moderate dementia who had previously had a cerebral infarction verified by neuroimaging showed statistically significant and clinically relevant benefits of EGb 761.
evidence level1
citationFeng JX (2026)
source<i>Ginkgo biloba</i> extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials.
topicGinkgo Cognition Meta-Analysis
claimIntroduction Ginkgo biloba leaf extracts belong to the most popular herbal medicines for the treatment of neurological disorders, including Alzheimer's disease (AD) or stroke.
evidence level1
citationFeng JX (2026)
source<i>Ginkgo biloba</i> extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials.
topicGinkgo Cognition Meta-Analysis
claimEGb 761, a proprietary ginkgo leaf extract, has been shown to improve brain cell energy supply, to enhance neurogenesis and neuroplasticity, to decrease blood viscosity and improve brain perfusion.
evidence level1
citationFeng JX (2026)
source<i>Ginkgo biloba</i> extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials.
topicGinkgo Cognition Meta-Analysis
claimIn addition, an overview of systematic reviews synthesized the broader EGb 761 evidence base across indications and highlighted that conclusions require caution given the methodological limitations of many reviews [].
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?
topicGinkgo Cognition Meta-Analysis
claimReal-world observational analyses have also reported associations between prescriptions of Ginkgo leaf extract and reduced risk of dementia severity progression, albeit with the inherent limitations of non-randomized designs [].
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?
topicGinkgo Cognition Meta-Analysis
claimAccordingly, this review revisits the historical evidence base with explicit attention to heterogeneity and methodological design, and then examines biomarker-confirmed AD-spectrum studies as a potential pivot point.
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?
topicGinkgo Cognition Meta-Analysis
claim1 2 Alzheimer’s disease (AD) remains the most common cause of dementia and continues to impose a major burden on patients, caregivers, and healthcare systems [].
evidence level3
citationYang YoungSoon (2026)
sourceGinkgo Biloba for Alzheimer’s Disease: From Mixed Dementia Trials to Biomarker-Confirmed Mild Cognitive Impairment—What Have We Learned over Two Decades, and Is There Finally a Bit of Hope?