Structured evidence table for Curcumin Depression Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Curcumin Depression Randomized Trial | Background Diabetic retinopathy (DR) is a significant complication of diabetes that can adversely affect the quality of life and anthropometric indices of individuals. | 2 | Amini S (2026) | The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial. |
| Curcumin Depression Randomized Trial | This study aimed to investigate the impact of a combination of curcumin and piperine on mental health status (stress, anxiety, and depression), sleep quality, and anthropometric indices in patients with non-proliferative diabetic retinopathy. | 2 | Amini S (2026) | The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial. |
| Curcumin Depression Randomized Trial | Furthermore, MDD is linked to a higher risk of developing other conditions like diabetes, heart disease, and stroke, which add to its overall impact on health (). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Curcumin Depression Randomized Trial | Neuroimaging studies have identified key pathological features of MDD, including reduced structural volumes in both cortical and subcortical areas, decreased gray matter volume, and significant alterations in the size and density of microglial cells (,). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Curcumin Depression Randomized Trial | These changes are also associated with abnormal neurotransmitter regulation and disruptions in gut microbiota (). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Curcumin Depression Randomized Trial | 1 2 3 4 5 6 7 8 9 10 11 12 Major depressive disorder (MDD) is a prevalent psychiatric condition impacting approximately 185 million individuals worldwide (). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
Source documents