Creatine Sleep Randomized Trial Evidence Table

Structured evidence table for Creatine Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Creatine Sleep Randomized TrialThis analysis investigated whether the dose or duration of CrM was associated with SEs.2Gonzalez DE (2026)Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials.
Creatine Sleep Randomized TrialAlthough dose and duration tertiles were statistically associated with study-level side effect reporting, the effect sizes were uniformly small, events were infrequent, and the reported symptoms were primarily mild and nonspecific.2Gonzalez DE (2026)Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials.
Creatine Sleep Randomized TrialNo consistent exposure-response pattern indicative of clinically meaningful risk was observed.2Gonzalez DE (2026)Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials.
Creatine Sleep Randomized TrialThere are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo.2Gonzalez DE (2026)Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials.
Creatine Sleep Randomized TrialThe present study investigates whether supplementation of a lower dose is associated with cognitive effects during sleep deprivation, focusing exclusively on cognitive performance outcomes.4Gordji-Nejad A (2026)Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.
Creatine Sleep Randomized TrialConclusions: Our results show that a dose of 0.2 g/kg creatine is associated with a reduced deterioration in cognitive performance during sleep deprivation.4Gordji-Nejad A (2026)Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.
Creatine Sleep Randomized TrialBackground/Objectives: Creatine is a supplement that, beyond its physiological effects, has been shown to have positive effects on cognitive abilities.4Gordji-Nejad A (2026)Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.
Creatine Sleep Randomized TrialIn our previous study, we showed that a single dose of 0.35 g/kg creatine induces changes in brain metabolism during sleep deprivation and reduces deterioration in cognitive performance.4Gordji-Nejad A (2026)Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.

Source documents

  1. Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials.
  2. Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.