Structured evidence table for Creatine Sleep Onset Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Creatine Sleep Onset Randomized Trial | The importance of the timing of Cr administration is based on the assumption that exercise-induced physiological changes, such as increased hyperemia and altered transport dynamics, may optimize tissue absorption and storage []. | 2 | Ben Maaoui Khouloud (2026) | Acute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial |
| Creatine Sleep Onset Randomized Trial | Yet, evidence supporting specific timing strategies is restricted to a few chronic studies with conflicting findings [,,]. | 2 | Ben Maaoui Khouloud (2026) | Acute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial |
| Creatine Sleep Onset Randomized Trial | [] found distinct differences between pre- and post-exercise ingestion regarding strength and hypertrophy over a 32-week intervention in older adults. | 2 | Ben Maaoui Khouloud (2026) | Acute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial |
| Creatine Sleep Onset Randomized Trial | 1 2 3 3 4 5 6 7 Creatine (Cr) (α-methyl guanidino-acetic acid) is primarily synthesized endogenously in the kidneys and liver [,]. | 2 | Ben Maaoui Khouloud (2026) | Acute Creatine Ingestion Before Resistance Training Enhances Strength Performance More than Ingestion During or After Training: A Randomized Crossover Pilot Trial |
| Creatine Sleep Onset Randomized Trial | Introduction Insufficient sleep increases the risk of weight gain and metabolic dysfunction, while obesity is linked to disrupted sleep and metabolic impairment. | 4 | Good L (2026) | Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults. |
| Creatine Sleep Onset Randomized Trial | Results In response to TSD compared with NS, tryptophan levels increased (+12%, FDR Conclusions Acute sleep loss elicits both shared and body-weight-specific changes in circulating metabolites in young adults. | 4 | Good L (2026) | Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults. |
| Creatine Sleep Onset Randomized Trial | Given that acute sleep loss is a common metabolic stressor that increases cardiometabolic risk, these differences may contribute to mechanistic hypotheses about the heightened vulnerability to metabolic dysregulation in individuals with obesity who are frequently exposed to sleep loss. | 4 | Good L (2026) | Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults. |
| Creatine Sleep Onset Randomized Trial | Although both conditions are tightly interconnected, it remains unclear whether body weight status determines how acute sleep loss alters metabolite levels. | 4 | Good L (2026) | Body-weight-specific and shared metabolomic responses to acute sleep loss in young adults. |
Source documents