topicCreatine Older Adults Cognition Meta-Analysis
claimThese changes contribute to increased sarcopenia risk during and after the menopausal transition, with implications for physical function, frailty, and long-term musculoskeletal health [].
evidence level1
citationNaddafha Siavash (2026)
sourceCreatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis
topicCreatine Older Adults Cognition Meta-Analysis
claimIn addition, creatine may exert direct anabolic or anticatabolic effects on muscle cells and influence bone via increased muscle pulling forces or direct cell signaling in osteoblasts [].
evidence level1
citationNaddafha Siavash (2026)
sourceCreatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis
topicCreatine Older Adults Cognition Meta-Analysis
claimFor example, a 12-week RCT reported that creatine (5 g/day) with RT significantly increased muscle strength and fat-free mass in women aged ~65 years [].
evidence level1
citationNaddafha Siavash (2026)
sourceCreatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis
topicCreatine Older Adults Cognition Meta-Analysis
claim1 2 3 4 5 6 6 Muscle and bone loss accelerate during the postmenopausal years due to aging and estrogen deficiency.
evidence level1
citationNaddafha Siavash (2026)
sourceCreatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis
topicCreatine Older Adults Cognition Meta-Analysis
claimCommentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.
evidence level1
citationCitherlet T (2026)
sourceCommentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.