Structured evidence table for Creatine Mental Fatigue Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Creatine Mental Fatigue Meta-Analysis | This “lactate–pyruvate shuttle” improves energy efficiency and limits the accumulation of metabolites associated with muscle fatigue []. | 3 | Larrea Ane (2026) | Revision of Energy Metabolism Adaptations in High-Level Athletes: From Physical Performance Enhancement to Potential Therapeutic Targets in Mental Disorders |
| Creatine Mental Fatigue Meta-Analysis | Improvements are also observed in respiratory chain efficiency, with increased activity of complexes I–IV and ATP synthase, reducing uncoupling and oxidative stress []. | 3 | Larrea Ane (2026) | Revision of Energy Metabolism Adaptations in High-Level Athletes: From Physical Performance Enhancement to Potential Therapeutic Targets in Mental Disorders |
| Creatine Mental Fatigue Meta-Analysis | Other dietary-derived compounds promote both mitophagy and biogenesis, leading to improved energy efficiency and muscle recovery []. | 3 | Larrea Ane (2026) | Revision of Energy Metabolism Adaptations in High-Level Athletes: From Physical Performance Enhancement to Potential Therapeutic Targets in Mental Disorders |
| Creatine Mental Fatigue Meta-Analysis | 1 2 3 1 High-level athletic performance depends on the organism’s ability to generate and utilize energy efficiently and sustainably, which varies according to the intensity, duration, and modality of exercise. | 3 | Larrea Ane (2026) | Revision of Energy Metabolism Adaptations in High-Level Athletes: From Physical Performance Enhancement to Potential Therapeutic Targets in Mental Disorders |
| Creatine Mental Fatigue Meta-Analysis | [] identified improvements in muscular strength, repeated sprint performance, power output, and fatigue resistance due to increased PCr availability, providing strong scientific support for creatine supplementation in athletic populations. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
| Creatine Mental Fatigue Meta-Analysis | There is also some evidence to suggest that short-term CrM supplementation (i.e. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
| Creatine Mental Fatigue Meta-Analysis | [] demonstrated improved repeated cycling performance following five days of CrM (4 × 5 g/day), suggesting a higher sustained power output during repeated cycling sessions. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
| Creatine Mental Fatigue Meta-Analysis | N N 1 2 3 1 Figure 1 2 4 5 2 2 1 6 1,6–11 Creatine (-(aminoiminomethyl)--methyl glycine) is a naturally occurring compound synthesised in the body from glycine, arginine, and methionine and can also be obtained from animal-based proteins or commercially available dietary supplements. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
Source documents