Structured evidence table for Collagen Supplementation Bone Density Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Collagen Supplementation Bone Density Randomized Trial | It typically leads to increased fat accumulation, especially visceral fat around the organs, and a reduction in lean muscle mass [,]. | 2 | Duangjai Acharaporn (2025) | Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women—A Randomized Controlled Study |
| Collagen Supplementation Bone Density Randomized Trial | The decline in estrogen levels contributes to bone density loss, raising the risk of osteoporosis []. | 2 | Duangjai Acharaporn (2025) | Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women—A Randomized Controlled Study |
| Collagen Supplementation Bone Density Randomized Trial | The calculation indicated a minimum of 17 participants per group, and to account for potential attrition, we increased the sample size by 20% following methodological recommendations []. | 2 | Duangjai Acharaporn (2025) | Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women—A Randomized Controlled Study |
| Collagen Supplementation Bone Density Randomized Trial | 1 2 3 4 4 Menopause plays a major role in altering a woman’s body composition. | 2 | Duangjai Acharaporn (2025) | Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women—A Randomized Controlled Study |
| Collagen Supplementation Bone Density Randomized Trial | Background High-carbohydrate high-fat (HCHF) diets have been associated with oxidative stress, impaired bone remodelling, and deterioration of skeletal integrity. | 4 | Ekeuku SO (2026) | Kelulut Honey Modulates Skeletal Health and Bone-Related Molecular Markers in Rats Fed a High-Carbohydrate and High-Fat Diet. |
| Collagen Supplementation Bone Density Randomized Trial | (3) Results: HCHF feeding reduced BMD, load, stress, Young's modulus, gluthatione peroxidase (GPx) activity, and superoxide dismutase (SOD) activity while increasing strain, displacement, serum C-terminal telopeptide of type 1 collagen (CTX-1) and receptor activator of nuclear factor-κB (RANK) levels, and runt-related transcription factor 2 ( Runx2 ) expression. | 4 | Ekeuku SO (2026) | Kelulut Honey Modulates Skeletal Health and Bone-Related Molecular Markers in Rats Fed a High-Carbohydrate and High-Fat Diet. |
| Collagen Supplementation Bone Density Randomized Trial | KH supplementation improved bone health by dose-dependently enhancing antioxidant defences, significantly increasing GPx and SOD activities, while catalase (CAT) activity was elevated at 600 mg/kg. | 4 | Ekeuku SO (2026) | Kelulut Honey Modulates Skeletal Health and Bone-Related Molecular Markers in Rats Fed a High-Carbohydrate and High-Fat Diet. |
| Collagen Supplementation Bone Density Randomized Trial | Kelulut honey (KH), a stingless bee honey rich in antioxidant compounds, has demonstrated protective effects against bone loss; however, its effects on bone density, biomechanical properties, antioxidant status, and bone-related molecular markers remain incompletely understood. | 4 | Ekeuku SO (2026) | Kelulut Honey Modulates Skeletal Health and Bone-Related Molecular Markers in Rats Fed a High-Carbohydrate and High-Fat Diet. |
Source documents