evidence table
Collagen Skin Hydration Randomized Trial Evidence Table
Structured evidence table for Collagen Skin Hydration Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Collagen Skin Hydration Randomized Trial | 1 2 3 4 5 6 7 8 9 Skin aging is a multifactorial biological process characterized by progressive alterations in skin structure, function, and appearance, including wrinkle formation, reduced hydration, impaired barrier integrity, and loss of elasticity [,]. | 2 | Hur Nayon (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women |
| Collagen Skin Hydration Randomized Trial | Impairment of the epidermal barrier, reflected by increased transepidermal water loss (TEWL), further exacerbates skin dryness and vulnerability to environmental stressors [,]. | 2 | Hur Nayon (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women |
| Collagen Skin Hydration Randomized Trial | 10 11 9 12 13 10 14 15 Growing evidence indicates that nutrition plays a critical role in skin homeostasis and aging [,]. | 2 | Hur Nayon (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women |
| Collagen Skin Hydration Randomized Trial | These changes are driven by intrinsic aging as well as extrinsic factors, particularly ultraviolet (UV) exposure, which promotes oxidative stress, chronic low-grade inflammation, and degradation of extracellular matrix components such as collagen and elastin [,,]. | 2 | Hur Nayon (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women |
| Collagen Skin Hydration Randomized Trial | Objective This study aimed to determine whether liposomal delivery enhances the effects of a collagen tripeptide-containing formulation on dermal structural and biomechanical parameters, as well as appearance-related skin properties, compared with a nonliposomal formulation and placebo. | 2 | Lin YK (2026) | Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial. |
| Collagen Skin Hydration Randomized Trial | Methods In a randomized, double-blind, placebo-controlled trial, 75 healthy adults aged 25-65 years were assigned to receive placebo, a nonliposomal formulation containing collagen tripeptides, or a liposomal formulation containing collagen tripeptides (50 mL/day) for 8 weeks. | 2 | Lin YK (2026) | Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial. |
Source documents
- A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
- Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.