evidence table

Collagen Skin Hydration Randomized Trial Evidence Table

Structured evidence table for Collagen Skin Hydration Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Collagen Skin Hydration Randomized Trial1 2 3 4 5 6 7 8 9 Skin aging is a multifactorial biological process characterized by progressive alterations in skin structure, function, and appearance, including wrinkle formation, reduced hydration, impaired barrier integrity, and loss of elasticity [,].2Hur Nayon (2026)A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
Collagen Skin Hydration Randomized TrialImpairment of the epidermal barrier, reflected by increased transepidermal water loss (TEWL), further exacerbates skin dryness and vulnerability to environmental stressors [,].2Hur Nayon (2026)A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
Collagen Skin Hydration Randomized Trial10 11 9 12 13 10 14 15 Growing evidence indicates that nutrition plays a critical role in skin homeostasis and aging [,].2Hur Nayon (2026)A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
Collagen Skin Hydration Randomized TrialThese changes are driven by intrinsic aging as well as extrinsic factors, particularly ultraviolet (UV) exposure, which promotes oxidative stress, chronic low-grade inflammation, and degradation of extracellular matrix components such as collagen and elastin [,,].2Hur Nayon (2026)A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
Collagen Skin Hydration Randomized TrialObjective This study aimed to determine whether liposomal delivery enhances the effects of a collagen tripeptide-containing formulation on dermal structural and biomechanical parameters, as well as appearance-related skin properties, compared with a nonliposomal formulation and placebo.2Lin YK (2026)Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.
Collagen Skin Hydration Randomized TrialMethods In a randomized, double-blind, placebo-controlled trial, 75 healthy adults aged 25-65 years were assigned to receive placebo, a nonliposomal formulation containing collagen tripeptides, or a liposomal formulation containing collagen tripeptides (50 mL/day) for 8 weeks.2Lin YK (2026)Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicCollagen Skin Hydration Randomized Trial
claim1 2 3 4 5 6 7 8 9 Skin aging is a multifactorial biological process characterized by progressive alterations in skin structure, function, and appearance, including wrinkle formation, reduced hydration, impaired barrier integrity, and loss of elasticity [,].
evidence level2
citationHur Nayon (2026)
sourceA Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
topicCollagen Skin Hydration Randomized Trial
claimImpairment of the epidermal barrier, reflected by increased transepidermal water loss (TEWL), further exacerbates skin dryness and vulnerability to environmental stressors [,].
evidence level2
citationHur Nayon (2026)
sourceA Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
topicCollagen Skin Hydration Randomized Trial
claim10 11 9 12 13 10 14 15 Growing evidence indicates that nutrition plays a critical role in skin homeostasis and aging [,].
evidence level2
citationHur Nayon (2026)
sourceA Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
topicCollagen Skin Hydration Randomized Trial
claimThese changes are driven by intrinsic aging as well as extrinsic factors, particularly ultraviolet (UV) exposure, which promotes oxidative stress, chronic low-grade inflammation, and degradation of extracellular matrix components such as collagen and elastin [,,].
evidence level2
citationHur Nayon (2026)
sourceA Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
topicCollagen Skin Hydration Randomized Trial
claimObjective This study aimed to determine whether liposomal delivery enhances the effects of a collagen tripeptide-containing formulation on dermal structural and biomechanical parameters, as well as appearance-related skin properties, compared with a nonliposomal formulation and placebo.
evidence level2
citationLin YK (2026)
sourceLiposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicCollagen Skin Hydration Randomized Trial
claimMethods In a randomized, double-blind, placebo-controlled trial, 75 healthy adults aged 25-65 years were assigned to receive placebo, a nonliposomal formulation containing collagen tripeptides, or a liposomal formulation containing collagen tripeptides (50 mL/day) for 8 weeks.
evidence level2
citationLin YK (2026)
sourceLiposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.

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Source documents

  1. A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral Centella asiatica Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women
  2. Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial.