Structured evidence table for Collagen Supplements and Skin, generated from 3 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Collagen Supplements and Skin | Background Centella asiatica has been widely recognized for its dermatological benefits; however, clinical evidence supporting the efficacy of oral supplementation for improving skin aging parameters remains limited. | 2 | Hur N (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral <i>Centella asiatica</i> Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women. |
| Collagen Supplements and Skin | Maximum wrinkle depth and total wrinkle volume were reduced by 13.3% and 13.7%, respectively, while surface roughness (Ra) decreased by 10.4%. | 2 | Hur N (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral <i>Centella asiatica</i> Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women. |
| Collagen Supplements and Skin | Epidermal hydration at the cheek site significantly increased, while transepidermal water loss decreased, indicating improved skin barrier function. | 2 | Hur N (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral <i>Centella asiatica</i> Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women. |
| Collagen Supplements and Skin | This randomized, double-blind, placebo-controlled study evaluated the effects of oral Centella asiatica extract on skin wrinkles and related skin parameters in middle-aged women. | 2 | Hur N (2026) | A Randomized, Double-Blind, Placebo-Controlled Trial Assessing the Effects of Oral <i>Centella asiatica</i> Extract on Skin Aging-Related Parameters in Middle-Aged Korean Women. |
| Collagen Supplements and Skin | Objective This study aimed to determine whether liposomal delivery enhances the effects of a collagen tripeptide-containing formulation on dermal structural and biomechanical parameters, as well as appearance-related skin properties, compared with a nonliposomal formulation and placebo. | 2 | Lin YK (2026) | Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial. |
| Collagen Supplements and Skin | Methods In a randomized, double-blind, placebo-controlled trial, 75 healthy adults aged 25-65 years were assigned to receive placebo, a nonliposomal formulation containing collagen tripeptides, or a liposomal formulation containing collagen tripeptides (50 mL/day) for 8 weeks. | 2 | Lin YK (2026) | Liposomal Delivery Enhances the Effects of a Collagen Tripeptide-Containing Formulation on Dermal Structure and Optical Skin Parameters: A Randomized, Double-Blind, Placebo-Controlled Trial. |
| Collagen Supplements and Skin | Collagen, along with antioxidants such as curcumin and glutathione, have gained increased utilization/awareness in recent years, providing dermal health benefits especially in women who experience declining or loss of estrogen with aging. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
| Collagen Supplements and Skin | The evidence of oral collagen as a nutraceutical is robust for improving several aspects of dermal health. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
| Collagen Supplements and Skin | For example, the epidermis is without a blood supply and does not have the same circulation and nutrient delivery found in the dermis [–]. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
| Collagen Supplements and Skin | The present narrative review is an extension of a larger project that covered polyphenols and phytoestrogens. | 4 | Arbex Priscila (2026) | Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels —A Narrative Review |
Source documents