Collagen Peptides Tendon Randomized Trial Evidence Table

Structured evidence table for Collagen Peptides Tendon Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Collagen Peptides Tendon Randomized TrialObjective To evaluate clinical evidence on oral or injectable hydrolyzed collagen peptides, or related low-molecular-weight peptide preparations, in tendon and ligament injuries and post-repair/reconstruction settings.1Latini L (2026)Clinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
Collagen Peptides Tendon Randomized TrialClosely related disorders were included only as contextual evidence when direct injury-specific data were limited.1Latini L (2026)Clinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
Collagen Peptides Tendon Randomized TrialThree provided direct evidence in tear or post-surgical populations: one pilot study of injectable low-molecular-weight peptides in partial supraspinatus tendon tears, one randomized trial after ACL reconstruction, and one randomized trial after rotator cuff repair.1Latini L (2026)Clinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
Collagen Peptides Tendon Randomized TrialBackground Low-molecular-weight hydrolyzed collagen peptides are increasingly used as adjuncts in musculoskeletal medicine, but their clinical role in tendon and ligament injuries remains unclear.1Latini L (2026)Clinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
Collagen Peptides Tendon Randomized TrialBackground Lateral elbow tendinopathy (LET) is a common upper-limb musculoskeletal disorder causing pain during gripping activities, reduced work capacity, and functional limitation.4Vitale N (2026)Ultrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
Collagen Peptides Tendon Randomized TrialResults PRTEE pain improved by 31.2 points (95% CI 22.2-40.2; Cohen's d_z = 2.48) and PRTEE function by 32.6 points (95% CI 26.7-38.5; d_z = 3.95).4Vitale N (2026)Ultrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
Collagen Peptides Tendon Randomized TrialMean maximal strength and maximal strength improved by 4.61 kg (95% CI 2.89-6.32) and 4.02 kg (95% CI 2.36-5.68), respectively.4Vitale N (2026)Ultrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
Collagen Peptides Tendon Randomized TrialLET is currently considered a predominantly degenerative condition characterized by collagen disorganization, extracellular matrix changes, neovascularization, and impaired tendon healing.4Vitale N (2026)Ultrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
topicCollagen Peptides Tendon Randomized Trial
claimObjective To evaluate clinical evidence on oral or injectable hydrolyzed collagen peptides, or related low-molecular-weight peptide preparations, in tendon and ligament injuries and post-repair/reconstruction settings.
evidence level1
citationLatini L (2026)
sourceClinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
topicCollagen Peptides Tendon Randomized Trial
claimClosely related disorders were included only as contextual evidence when direct injury-specific data were limited.
evidence level1
citationLatini L (2026)
sourceClinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
topicCollagen Peptides Tendon Randomized Trial
claimThree provided direct evidence in tear or post-surgical populations: one pilot study of injectable low-molecular-weight peptides in partial supraspinatus tendon tears, one randomized trial after ACL reconstruction, and one randomized trial after rotator cuff repair.
evidence level1
citationLatini L (2026)
sourceClinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
topicCollagen Peptides Tendon Randomized Trial
claimBackground Low-molecular-weight hydrolyzed collagen peptides are increasingly used as adjuncts in musculoskeletal medicine, but their clinical role in tendon and ligament injuries remains unclear.
evidence level1
citationLatini L (2026)
sourceClinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
topicCollagen Peptides Tendon Randomized Trial
claimBackground Lateral elbow tendinopathy (LET) is a common upper-limb musculoskeletal disorder causing pain during gripping activities, reduced work capacity, and functional limitation.
evidence level4
citationVitale N (2026)
sourceUltrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
topicCollagen Peptides Tendon Randomized Trial
claimResults PRTEE pain improved by 31.2 points (95% CI 22.2-40.2; Cohen's d_z = 2.48) and PRTEE function by 32.6 points (95% CI 26.7-38.5; d_z = 3.95).
evidence level4
citationVitale N (2026)
sourceUltrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
topicCollagen Peptides Tendon Randomized Trial
claimMean maximal strength and maximal strength improved by 4.61 kg (95% CI 2.89-6.32) and 4.02 kg (95% CI 2.36-5.68), respectively.
evidence level4
citationVitale N (2026)
sourceUltrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.
topicCollagen Peptides Tendon Randomized Trial
claimLET is currently considered a predominantly degenerative condition characterized by collagen disorganization, extracellular matrix changes, neovascularization, and impaired tendon healing.
evidence level4
citationVitale N (2026)
sourceUltrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.

Source documents

  1. Clinical evidence for low-molecular-weight collagen peptides in tendon and ligament tears: a systematic review with narrative synthesis.
  2. Ultrasound-Guided Collagen Peptides Injections Combined with Focused Extracorporeal Shockwave Therapy and Therapeutic Exercise in Chronic Partial Common Extensor Tendon Tears at Elbow Lateral Epicondyle: A Retrospective Case Series.