topicCollagen Bone Health Randomized Trial
claimConclusion Within a 6-month healing interval, ACBP showed CBCT-based dimensional outcomes comparable to DBBM and a lower residual graft fraction with a similar vital bone fraction at implant placement, suggesting that the observed difference was more related to graft turnover than to greater bone formation.
evidence level2
citationRao S (2026)
sourcePartially demineralized allogeneic cancellous bone plug versus deproteinized bovine bone mineral for guided bone regeneration: a pilot randomized controlled clinical trial.
topicCollagen Bone Health Randomized Trial
claimClinical relevance At routine implant timing (~ 6 months), use of ACBP was associated with a lower residual graft fraction at re-entry while maintaining short-term CBCT-based dimensional stability.
evidence level2
citationRao S (2026)
sourcePartially demineralized allogeneic cancellous bone plug versus deproteinized bovine bone mineral for guided bone regeneration: a pilot randomized controlled clinical trial.
topicCollagen Bone Health Randomized Trial
claimObjectives To compare a partially demineralized allogeneic cancellous bone plug (ACBP) with deproteinized bovine bone mineral (DBBM) for guided bone regeneration (GBR), focusing on CBCT-based dimensional outcomes and histomorphometric tissue composition at implant placement.
evidence level2
citationRao S (2026)
sourcePartially demineralized allogeneic cancellous bone plug versus deproteinized bovine bone mineral for guided bone regeneration: a pilot randomized controlled clinical trial.
topicCollagen Bone Health Randomized Trial
claimMaterials and methods In this prospective randomized controlled clinical trial, 25 adults requiring GBR for two common indications-posterior maxillary sinus floor elevation or mandibular posterior extraction socket preservation-were randomized to ACBP (n = 12) or DBBM (n = 13), with collagen membrane coverage in both groups.
evidence level2
citationRao S (2026)
sourcePartially demineralized allogeneic cancellous bone plug versus deproteinized bovine bone mineral for guided bone regeneration: a pilot randomized controlled clinical trial.
topicCollagen Bone Health Randomized Trial
claimThis understanding could facilitate the development of improved protocols to support bone healing and to minimize atrophy.
evidence level2
citationHeselich Anja (2026)
sourceAlveolar Ridge Preservation Revisited: A Multimodal Evaluation of Bone Preservation and Regeneration—Preliminary Findings from a Randomized Controlled Clinical Trial
topicCollagen Bone Health Randomized Trial
claimOnly a limited number of comparative histological studies are available, and only a heterogenous selection of studies with radiological evaluations can be found.
evidence level2
citationHeselich Anja (2026)
sourceAlveolar Ridge Preservation Revisited: A Multimodal Evaluation of Bone Preservation and Regeneration—Preliminary Findings from a Randomized Controlled Clinical Trial
topicCollagen Bone Health Randomized Trial
claimVolume was determined by summing the cross-sectional areas of each slice and multiplying the result by the slice thickness.
evidence level2
citationHeselich Anja (2026)
sourceAlveolar Ridge Preservation Revisited: A Multimodal Evaluation of Bone Preservation and Regeneration—Preliminary Findings from a Randomized Controlled Clinical Trial
topicCollagen Bone Health Randomized Trial
claim1 2 3 4 5 6 7 8 9 Tooth loss can have various causes, with dental caries and periodontitis identified as the two main causes.
evidence level2
citationHeselich Anja (2026)
sourceAlveolar Ridge Preservation Revisited: A Multimodal Evaluation of Bone Preservation and Regeneration—Preliminary Findings from a Randomized Controlled Clinical Trial