Structured evidence table for Collagen Bone Health Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Collagen Bone Health Meta-Analysis | Menopause-associated estrogen deficiency has been implicated in cartilage degeneration and osteoarthritis (OA) progression. | 1 | Tehalia MK (2026) | Estrogen Deficiency in Menopause: A Major Contributor to Cartilage Degeneration and Osteoarthritis: A Systematic Review and Meta-Analysis. |
| Collagen Bone Health Meta-Analysis | This systematic review and meta-analysis evaluates evidence from human and animal studies. | 1 | Tehalia MK (2026) | Estrogen Deficiency in Menopause: A Major Contributor to Cartilage Degeneration and Osteoarthritis: A Systematic Review and Meta-Analysis. |
| Collagen Bone Health Meta-Analysis | Estrogen deficiency is associated with cartilage degeneration, with strong supportive evidence from OVX models. | 1 | Tehalia MK (2026) | Estrogen Deficiency in Menopause: A Major Contributor to Cartilage Degeneration and Osteoarthritis: A Systematic Review and Meta-Analysis. |
| Collagen Bone Health Meta-Analysis | Osteogenesis imperfecta (OI) is a rare genetic disorder most often caused by mutations in genes that encode collagen type I. | 1 | Patel P (2025) | Post-translational modifications of collagen type I in osteogenesis imperfecta: Systematic review and meta-analysis. |
| Collagen Bone Health Meta-Analysis | OI collagen-I differs from healthy collagen-I due to the underlying mutation and altered post-translational modifications (PTMs). | 1 | Patel P (2025) | Post-translational modifications of collagen type I in osteogenesis imperfecta: Systematic review and meta-analysis. |
Source documents