topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimFor functional factors supported by sufficient human evidence, stratified application can be made according to their primary effects.
evidence level3
citationHuang X (2026)
sourceMultimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts.
topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimMechanisms that specifically enhance physical strength include increased blood flow delivery via the NO-sGC-cGMP pathway, attenuation of central nervous system fatigue through LAT1-mediated tryptophan competition, and maintenance of calcium homeostasis via the SERCA-RyR1-VDAC1-MCU axis.
evidence level3
citationHuang X (2026)
sourceMultimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts.
topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimThis article provides a scoping review of various types of functional factors and their mechanisms of action in enhancing physical strength and endurance, focusing on their roles in regulating the central nervous system, improving energy metabolism, reducing metabolite accumulation, enhancing antioxidant and anti-inflammatory capacity, regulating the endocrine system, and improving blood circulation.
evidence level3
citationHuang X (2026)
sourceMultimechanistic actions of functional factors in enhancing physical strength and endurance: a scoping review of nutritional basis and natural extracts.
topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimThe glycolysis system utilizes energy substrates from blood glucose or glycogen storage in skeletal muscle, the former of which could be increased after acute carbohydrate supplementation.
evidence level4
citationThar Phyo Pyae (2026)
sourcePost-workout supplementation with CoQ10 and sports drink on exercise performance and muscle recovery after exercise in normal and overweight males
topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimThese differences were associated with an increased BMR in the overweight group compared with the normal group (​< ​0.01).
evidence level4
citationThar Phyo Pyae (2026)
sourcePost-workout supplementation with CoQ10 and sports drink on exercise performance and muscle recovery after exercise in normal and overweight males
topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimCompared with the placebo group, supplementation with CoQ10 or sports drink consumption significantly increased the absolute and relative values of resistance exercise volume in both groups (A–B).
evidence level4
citationThar Phyo Pyae (2026)
sourcePost-workout supplementation with CoQ10 and sports drink on exercise performance and muscle recovery after exercise in normal and overweight males
topicCoenzyme Q10 Muscle Fatigue Randomized Trial
claimThe main reasons for their use are to increase muscle mass, increase the rate of recovery, and improve exercise performance.
evidence level4
citationThar Phyo Pyae (2026)
sourcePost-workout supplementation with CoQ10 and sports drink on exercise performance and muscle recovery after exercise in normal and overweight males