Structured evidence table for Coenzyme Q10 Exercise Recovery Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Coenzyme Q10 Exercise Recovery Randomized Trial | Risk of bias was assessed using Revised Cochrane Risk-of-Bias Tool for Randomized Trials (RoB 2) and Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I V2), and methodological quality was appraised with the Mixed Methods Appraisal Tool (MMAT). | 1 | Wan Q (2026) | Effects of exercise training on skeletal muscle function in patients with mitochondrial myopathy: a systematic review. |
| Coenzyme Q10 Exercise Recovery Randomized Trial | Moderate-intensity aerobic and resistance exercise consistently improved maximal oxygen uptake (VO 2 max), maximal workload (W max), muscle strength, and mitochondrial enzyme activity, with no consistent group-level increases observed in creatine kinase (CK) levels or mtDNA mutation burden. | 1 | Wan Q (2026) | Effects of exercise training on skeletal muscle function in patients with mitochondrial myopathy: a systematic review. |
| Coenzyme Q10 Exercise Recovery Randomized Trial | Aerobic training enhanced oxidative capacity, phosphocreatine (PCr) recovery, and antioxidant defense, while resistance training improved muscle strength, satellite cell activation, and reduced cytochrome c oxidase (COX)-deficient fibers. | 1 | Wan Q (2026) | Effects of exercise training on skeletal muscle function in patients with mitochondrial myopathy: a systematic review. |
| Coenzyme Q10 Exercise Recovery Randomized Trial | Background Mitochondrial myopathy (MM) is a group of rare, progressive muscle disorders characterized by impaired oxidative phosphorylation due to mitochondrial DNA (mtDNA) or nuclear DNA (nDNA) mutations, leading to exercise intolerance, muscle weakness, and metabolic dysfunction. | 1 | Wan Q (2026) | Effects of exercise training on skeletal muscle function in patients with mitochondrial myopathy: a systematic review. |
| Coenzyme Q10 Exercise Recovery Randomized Trial | The results demonstrated that oral coenzyme Q10 elevated blood coenzyme Q10 concentration (standardized mean difference: 2.710, 95% confidence interval: 1.57-3.85, p < 0.00001) and reduced blood malondialdehyde concentration (standardized mean difference: -0.289, 95% confidence interval: -0.541 to -0.038, p = 0.024). | 1 | Zhang Y (2026) | Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review. |
| Coenzyme Q10 Exercise Recovery Randomized Trial | Additionally, oral coenzyme Q10 was found to reduce blood creatine kinase values (standardized mean difference: -1.532, 95% confidence interval: -2.856 to -0.209, p = 0.023), suggesting a potential protective effect on skeletal muscle. | 1 | Zhang Y (2026) | Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review. |
| Coenzyme Q10 Exercise Recovery Randomized Trial | Quantitative and qualitative analyses were performed.ResultsThe study screened 14 randomized controlled trials that included a total of 433 subjects. | 1 | Zhang Y (2026) | Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review. |
Source documents