topicCoenzyme Q10 Exercise Performance Randomized Trial
claimThe results demonstrated that oral coenzyme Q10 elevated blood coenzyme Q10 concentration (standardized mean difference: 2.710, 95% confidence interval: 1.57-3.85, p < 0.00001) and reduced blood malondialdehyde concentration (standardized mean difference: -0.289, 95% confidence interval: -0.541 to -0.038, p = 0.024).
evidence level1
citationZhang Y (2026)
sourceEffects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
topicCoenzyme Q10 Exercise Performance Randomized Trial
claimAdditionally, oral coenzyme Q10 was found to reduce blood creatine kinase values (standardized mean difference: -1.532, 95% confidence interval: -2.856 to -0.209, p = 0.023), suggesting a potential protective effect on skeletal muscle.
evidence level1
citationZhang Y (2026)
sourceEffects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
topicCoenzyme Q10 Exercise Performance Randomized Trial
claimQuantitative and qualitative analyses were performed.ResultsThe study screened 14 randomized controlled trials that included a total of 433 subjects.
evidence level1
citationZhang Y (2026)
sourceEffects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
topicCoenzyme Q10 Exercise Performance Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 Aging is associated with a gradual decline in the function of various cells and tissues, impacting multiple systems such as the musculoskeletal and cardiorespiratory systems, and consequently reducing quality of life [,].
evidence level4
citationBagheri Navid (2025)
sourceEffects of Coenzyme Q10 Supplementation on Physical Function Adaptations to High-Intensity Interval Training in Older Adults
topicCoenzyme Q10 Exercise Performance Randomized Trial
claimWith age, body fat distribution shifts and accumulates, heightening the risk of metabolic diseases [].
evidence level4
citationBagheri Navid (2025)
sourceEffects of Coenzyme Q10 Supplementation on Physical Function Adaptations to High-Intensity Interval Training in Older Adults
topicCoenzyme Q10 Exercise Performance Randomized Trial
claimAs a result, older adults often experience increased fatigue and a higher risk of falls during daily activities, further diminishing their overall quality of life [,,].
evidence level4
citationBagheri Navid (2025)
sourceEffects of Coenzyme Q10 Supplementation on Physical Function Adaptations to High-Intensity Interval Training in Older Adults