topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimRisk of bias was assessed using RoB 2, ROBINS-I, and AMSTAR 2; certainty of evidence was graded with GRADE.
evidence level2
citationWyss F (2026)
sourceIbero-American position statement on therapeutic recommendations for the preventive management of cardiovascular complications in latin-American patients with type 2 diabetes mellitus: consensus of the prevention council of the inter-American society of cardiology (SIAC-PREVENT).
topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimT2DM confers a 2–4-fold increased cardiovascular risk and higher rates of stroke and heart failure.
evidence level2
citationWyss F (2026)
sourceIbero-American position statement on therapeutic recommendations for the preventive management of cardiovascular complications in latin-American patients with type 2 diabetes mellitus: consensus of the prevention council of the inter-American society of cardiology (SIAC-PREVENT).
topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimCONCLUSIONS: This Ibero-American position statement supports an evidence-based and equity-oriented approach to preventing cardiovascular complications in people with T2DM in Latin America and the Caribbean.
evidence level2
citationWyss F (2026)
sourceIbero-American position statement on therapeutic recommendations for the preventive management of cardiovascular complications in latin-American patients with type 2 diabetes mellitus: consensus of the prevention council of the inter-American society of cardiology (SIAC-PREVENT).
topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimBACKGROUND: Type 2 diabetes mellitus (T2DM) affects an estimated 463 million adults worldwide, nearly 80% of whom live in low- and middle-income countries.
evidence level2
citationWyss F (2026)
sourceIbero-American position statement on therapeutic recommendations for the preventive management of cardiovascular complications in latin-American patients with type 2 diabetes mellitus: consensus of the prevention council of the inter-American society of cardiology (SIAC-PREVENT).
topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimHowever, most prior studies have assumed high-dose intake for ergogenic purposes, and evidence on the effects of low-dose interventions in generally healthy Japanese adults with a tendency toward constipation remains limited.
evidence level2
citationOtsubo Y (2026)
sourceEffects of low-dose medium-chain triglycerides on bowel habit outcomes in Japanese adults prone to constipation: a randomized, double-blind, LCT-controlled crossover trial.
topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimConclusion Daily intake of even a small amount of MCTs, compared with LCTs, may be helpful in improving bowel movements in Japanese adults prone to constipation.
evidence level2
citationOtsubo Y (2026)
sourceEffects of low-dose medium-chain triglycerides on bowel habit outcomes in Japanese adults prone to constipation: a randomized, double-blind, LCT-controlled crossover trial.
topicCoconut-Water Sleep Healthy Adults Randomized Trial
claimMedium-chain triglycerides (MCTs), composed solely of medium-chain fatty acids, have been suggested to improve bowel movements in athletes.
evidence level2
citationOtsubo Y (2026)
sourceEffects of low-dose medium-chain triglycerides on bowel habit outcomes in Japanese adults prone to constipation: a randomized, double-blind, LCT-controlled crossover trial.