topicCocoa Cardiovascular Meta-Analysis
claim1 2 3 4 5 Metabolic syndrome (MetS) is characterized by the coexistence of cardiovascular risk factors and metabolic disorders, such as hypertension, insulin resistance, dyslipidemias – elevated triglyceride levels and reduced HDL levels – and increased waist circumference [,].
evidence level1
citationGomes Chagas Amanda (2026)
sourceThe effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis
topicCocoa Cardiovascular Meta-Analysis
claimThe presence of MetS is a risk factor for other conditions, particularly increasing the risk of developing type 2 diabetes (DM2) by five times and the risk of cardiovascular diseases by three times [].
evidence level1
citationGomes Chagas Amanda (2026)
sourceThe effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis
topicCocoa Cardiovascular Meta-Analysis
claimIt may be the result from a combination of genetic factors, dietary profile, and physical inactivity [].
evidence level1
citationGomes Chagas Amanda (2026)
sourceThe effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis
topicCocoa Cardiovascular Meta-Analysis
claimAmong the different forms of the disease, type 2 diabetes mellitus (T2D) accounts for approximately 90–95% of all cases and is strongly associated with insulin resistance, excess adiposity, physical inactivity, and dietary patterns characterized by high consumption of energy-dense, highly processed foods [,].
evidence level3
citationTornero-Aguilera Jose Francisco (2026)
sourceCocoa-Based Plant Matrices in Glucose Metabolism: Bioactive Compounds and Redox Signaling
topicCocoa Cardiovascular Meta-Analysis
claim6 7 8 Over the past decades, the prevalence of diabetes has increased markedly worldwide, reaching levels of major public health concern.
evidence level3
citationTornero-Aguilera Jose Francisco (2026)
sourceCocoa-Based Plant Matrices in Glucose Metabolism: Bioactive Compounds and Redox Signaling
topicCocoa Cardiovascular Meta-Analysis
claimThe disease imposes a substantial economic burden on healthcare systems, reduces quality of life, and is associated with a marked increase in mortality risk.
evidence level3
citationTornero-Aguilera Jose Francisco (2026)
sourceCocoa-Based Plant Matrices in Glucose Metabolism: Bioactive Compounds and Redox Signaling
topicCocoa Cardiovascular Meta-Analysis
claim1 2 3 4 5 Diabetes mellitus comprises a complex and heterogeneous group of metabolic disorders characterized by chronic hyperglycemia resulting from alterations in insulin secretion, insulin action, or a combination of both processes.
evidence level3
citationTornero-Aguilera Jose Francisco (2026)
sourceCocoa-Based Plant Matrices in Glucose Metabolism: Bioactive Compounds and Redox Signaling