topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claimThese conditions are recognized as major risk factors for various diseases, including cardiovascular and metabolic disorders (World Obesity Federation ) and contribute to an estimated 2.8 million deaths annually due to obesity‐related complications (World Health Organization ).
evidence level3
citationForgerini Marcela (2025)
sourceHerbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claim2004 2015 2020 2009 2020 2022 Notably, 2 previous systematic reviews (2004 and 2015) highlighted that most herbal medicinal products commonly used by the Brazilian population lack robust scientific evidence supporting their efficacy for weight loss (Pittler and Ernst ; Cercato et al. ).
evidence level3
citationForgerini Marcela (2025)
sourceHerbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claimConversely, four other reviews identified herbal medicinal products associated with favorable outcomes in reducing anthropometric indices in humans and animals (Payab et al. ; Hasani‐Ranjbar et al. ; Maunder et al. ; Park et al. ).
evidence level3
citationForgerini Marcela (2025)
sourceHerbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claim2023 2020 2023 2021 Obesity and overweight are highly prevalent health conditions, affecting approximately 813 million adults worldwide and imposing substantial economic burdens on health systems—amounting to approximately USD 1.96 trillion globally in 2020 (World Obesity Federation ) and BRL 1.39 billion for the Brazilian health system (Nilson et al. ).
evidence level3
citationForgerini Marcela (2025)
sourceHerbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claim1 2 3 5 6 7 8 9 More than two billion people are at risk of micronutrient deficiencies, which often involve multiple, rather than single, nutrients [,].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claimThey are widely used to help individuals meet their daily nutrient requirements, support overall health, and address increased nutritional needs associated with pregnancy, aging, and illness.
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claimAccording to the National Health and Nutrition Examination Survey, MVM use in the USA increased from 35% in 1999-2000 [] to 49-52% between 2011 and 2014, with higher usage among women than men [-].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicCitrus Bioflavonoids Blood Pressure Meta-Analysis
claimThe most common deficiencies include vitamin A, folic acid, vitamin D, iron, iodine, and zinc, especially among children and women in low- and middle-income countries [-].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation