topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claim7 8 9 10 11 In addition to its essential oil, bergamot is a relevant source of polyphenols and flavonoids, including unique C-glycosyl flavonoids such as brutieridin and melitidin [], which have been associated with cardiometabolic, antioxidant, and anti-inflammatory effects [,,,].
evidence level3
citationDe Bruno Alessandra (2026)
sourceGreen Recovery of Bioactive Compounds from Bergamot ( Citrus bergamia ) By-Products: Sustainable Extraction, Food Applications, and Health-Promoting Properties
topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claimCurrently, most industrial residues are mainly destined for livestock feed or bioenergy production, despite evidence showing that bergamot pomace and peel-derived fractions exhibit high phenolic content and strong antioxidant activity, as assessed by commonly used spectrophotometric assays such as DPPH, ABTS, and FRAP [,,].
evidence level3
citationDe Bruno Alessandra (2026)
sourceGreen Recovery of Bioactive Compounds from Bergamot ( Citrus bergamia ) By-Products: Sustainable Extraction, Food Applications, and Health-Promoting Properties
topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claimEarlier studies were included only when they provided essential background information, methodological support, or relevant comparative evidence.
evidence level3
citationDe Bruno Alessandra (2026)
sourceGreen Recovery of Bioactive Compounds from Bergamot ( Citrus bergamia ) By-Products: Sustainable Extraction, Food Applications, and Health-Promoting Properties
topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claim1 2 3 The agri-food industry is increasingly required to adopt sustainable processing strategies to reduce waste, minimize environmental impact, and produce natural ingredients suitable for clean-label food products.
evidence level3
citationDe Bruno Alessandra (2026)
sourceGreen Recovery of Bioactive Compounds from Bergamot ( Citrus bergamia ) By-Products: Sustainable Extraction, Food Applications, and Health-Promoting Properties
topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claimCardiovascular disease (CVD) remains the leading cause of death worldwide, with elevated low-density lipoprotein cholesterol (LDL-C) as a major risk factor.
evidence level3
citationJacobo-Velázquez DA (2025)
sourceFunctional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index.
topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claimBuilding on these strategies, the CLCI is then proposed as a practical scoring system, analogous to the glycemic index for blood sugar, that integrates the evidence-based potency of ingredients, effective dosing, and synergistic interactions into a single metric.
evidence level3
citationJacobo-Velázquez DA (2025)
sourceFunctional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index.
topicCitrus Bergamot LDL Cholesterol Meta-Analysis
claimBeyond medications, dietary interventions and functional foods offer significant cholesterol-lowering potential.
evidence level3
citationJacobo-Velázquez DA (2025)
sourceFunctional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index.