Structured evidence table for Citrulline Malate Resistance Exercise Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Citrulline Malate Resistance Exercise Randomized Trial | Interpretation is further complicated by previous evidence syntheses that pooled studies of pure L-citrulline with CM, thereby limiting conclusions specific to CM supplementation [,,]. | 1 | Wang Xuexiang (2026) | Effects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis |
| Citrulline Malate Resistance Exercise Randomized Trial | In contrast, Aguiar & Casonatto (2022) [] focused exclusively on maximal muscular strength in resistance-trained adults incorporating four trials without distinguishing between acute and chronic supplementation protocols, and found no performance benefits. | 1 | Wang Xuexiang (2026) | Effects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis |
| Citrulline Malate Resistance Exercise Randomized Trial | These reviews therefore reach divergent conclusions and each addresses only a narrow aspect of the available evidence []. | 1 | Wang Xuexiang (2026) | Effects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis |
| Citrulline Malate Resistance Exercise Randomized Trial | 1 2 3 4 5 6 2 Citrulline malate (CM) is a popular dietary supplement marketed as an ergogenic aid for exercise performance []. | 1 | Wang Xuexiang (2026) | Effects of Citrulline Malate Supplementation on Exercise Performance: A Systematic Review and Three-Level Meta-Analysis |
| Citrulline Malate Resistance Exercise Randomized Trial | These changes include endothelial dysfunction, reduced nitric oxide (NO) bioavailability, increased arterial stiffness, loss of skeletal muscle mass and strength, and unfavorable shifts in body composition (Cauley, Albu et al.). | 3 | Chen Zhigang (2026) | L-citrulline as a nitric oxide–modulating therapeutic adjunct to exercise: effects on vascular function, arterial stiffness, and cardiometabolic health in postmenopausal and older women |
| Citrulline Malate Resistance Exercise Randomized Trial | From a vascular perspective, postmenopausal women frequently exhibit impaired endothelial-dependent vasodilation and increased central arterial stiffness, both of which contribute to exaggerated blood pressure responses during daily physical activity (Moreau and Hildreth). | 3 | Chen Zhigang (2026) | L-citrulline as a nitric oxide–modulating therapeutic adjunct to exercise: effects on vascular function, arterial stiffness, and cardiometabolic health in postmenopausal and older women |
| Citrulline Malate Resistance Exercise Randomized Trial | Reduced NO production, driven by diminished estrogen signaling and age-related endothelial dysfunction, plays a central role in these changes. | 3 | Chen Zhigang (2026) | L-citrulline as a nitric oxide–modulating therapeutic adjunct to exercise: effects on vascular function, arterial stiffness, and cardiometabolic health in postmenopausal and older women |
| Citrulline Malate Resistance Exercise Randomized Trial | 2023 2012 2013 2003 2014 2009 2008 Menopause is the permanent cessation of menstrual cycles, typically occurring around 45–55 years of age, marking the end of a woman’s reproductive period. | 3 | Chen Zhigang (2026) | L-citrulline as a nitric oxide–modulating therapeutic adjunct to exercise: effects on vascular function, arterial stiffness, and cardiometabolic health in postmenopausal and older women |
Source documents