topicCitrulline Hydration Exercise Randomized Trial
claimBackground: Post-COVID-19 syndrome is associated with endothelial dysfunction (ED) and various sequelae, particularly in individuals who experienced critical illness during the acute phase, affecting lung function and the musculoskeletal system.
evidence level2
citationFernanda SM (2026)
sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial.
topicCitrulline Hydration Exercise Randomized Trial
claimConclusions: L-citrulline supplementation for three months decreased ICAM-1 and increased 6MWT.
evidence level2
citationFernanda SM (2026)
sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial.
topicCitrulline Hydration Exercise Randomized Trial
claimL-citrulline, a nonessential amino acid, has been shown to improve endothelial function, systemic inflammation, blood pressure, and physical performance.
evidence level2
citationFernanda SM (2026)
sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial.
topicCitrulline Hydration Exercise Randomized Trial
claimNext, we integrate evidence on the ergogenic effects of various dietary interventions with existing knowledge on the perception of effort.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicCitrulline Hydration Exercise Randomized Trial
claimBeta-alanine, caffeine or carbohydrate mouth rinsing are examples of evidence-based ergogenic aids.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicCitrulline Hydration Exercise Randomized Trial
claimConclusion While current evidence supports a key role for dietary interventions on endurance performance by influencing individuals' perceived effort, more research is needed to determine the optimal doses and precise formulations for different sports, in order to employ a personalized strategy.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicCitrulline Hydration Exercise Randomized Trial
claimBackground Exercise tolerance is a pivotal factor in determining athletic competitive success, as well as mobility and quality of life in elderly individuals and those afflicted by chronic ailments.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.