Structured evidence table for Choline Cognition Meta-Analysis, generated from 1 reusable source document in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Choline Cognition Meta-Analysis | Study design Following a pre-registered protocol (CRD42023403879), we searched MEDLINE, EMBASE, and PsycINFO for studies reporting 1H-MRS choline levels in individuals with psychosis, clinical high risk (CHR) states, and healthy controls. | 1 | Fanshawe JB (2026) | Variability and Magnitude of Choline Levels Across the Psychosis Spectrum: A Meta-analysis. |
| Choline Cognition Meta-Analysis | Increased choline variability was observed in the dlPFC in psychosis cohorts and the mPFC and temporal lobe in CHR groups. | 1 | Fanshawe JB (2026) | Variability and Magnitude of Choline Levels Across the Psychosis Spectrum: A Meta-analysis. |
| Choline Cognition Meta-Analysis | Increased variability in psychosis and greater differences in treatment-resistant cohorts suggest increased choline levels might identify a subgroup who do not respond to dopamine antagonist treatment. | 1 | Fanshawe JB (2026) | Variability and Magnitude of Choline Levels Across the Psychosis Spectrum: A Meta-analysis. |
| Choline Cognition Meta-Analysis | Background and hypothesis Animal, post-mortem, and pharmacological studies suggest altered choline levels in psychosis. | 1 | Fanshawe JB (2026) | Variability and Magnitude of Choline Levels Across the Psychosis Spectrum: A Meta-analysis. |
Source documents