Structured evidence table for Chia-Lipid-Profile-Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Chia-Lipid-Profile-Meta-Analysis | Study quality was assessed using the Cochrane Risk of Bias 2 tool and the GRADE framework. | 1 | Zhao J (2026) | Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials. |
| Chia-Lipid-Profile-Meta-Analysis | Compared with control diets, KD significantly reduced triglycerides (WMD: -22.31 mg/dL; 95% CI: -28.90 to -15.72; p < 0.001; I2 = 69.8%, p < 0.001). | 1 | Zhao J (2026) | Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials. |
| Chia-Lipid-Profile-Meta-Analysis | HDL-C increased significantly (WMD: 3.52 mg/dL; 95% CI: 1.24 to 5.81; p < 0.001; I2 = 92.5%, p < 0.001). | 1 | Zhao J (2026) | Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials. |
| Chia-Lipid-Profile-Meta-Analysis | AIMS: The effects of the ketogenic diet (KD) on lipid metabolism remain controversial. | 1 | Zhao J (2026) | Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials. |
| Chia-Lipid-Profile-Meta-Analysis | It is often associated with hormonal imbalance, metabolic disturbances, and reproductive complications, which together contribute to an elevated risk of long-term cardiometabolic disorders. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
| Chia-Lipid-Profile-Meta-Analysis | To narratively synthesize mechanistic rationale and human clinical evidence on dietary seeds and selected nutraceuticals relevant to PCOS, with emphasis on metabolic and reproductive endpoints of interest to nutrition and obstetrics/gynecology practice. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
| Chia-Lipid-Profile-Meta-Analysis | Proposed "seed cycling" protocols have received attention, yet most clinical data are derived from mixed-seed supplementation studies or low-level evidence, such as case reports, and should be considered hypothesis-generating. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
| Chia-Lipid-Profile-Meta-Analysis | Polycystic ovary syndrome (PCOS) represents one of the most common endocrine disorders among women of reproductive age. | 4 | Singnale P (2026) | Role of Functional Foods and Nutraceutical Compounds in Alleviating Polycystic Ovary Syndrome: A Narrative Review. |
Source documents