Chia Cholesterol Meta-Analysis Evidence Table

Structured evidence table for Chia Cholesterol Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Chia Cholesterol Meta-AnalysisStudy quality was assessed using the Cochrane Risk of Bias 2 tool and the GRADE framework.1Zhao J (2026)Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
Chia Cholesterol Meta-AnalysisCompared with control diets, KD significantly reduced triglycerides (WMD: -22.31 mg/dL; 95% CI: -28.90 to -15.72; p < 0.001; I2 = 69.8%, p < 0.001).1Zhao J (2026)Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
Chia Cholesterol Meta-AnalysisHDL-C increased significantly (WMD: 3.52 mg/dL; 95% CI: 1.24 to 5.81; p < 0.001; I2 = 92.5%, p < 0.001).1Zhao J (2026)Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
Chia Cholesterol Meta-AnalysisAIMS: The effects of the ketogenic diet (KD) on lipid metabolism remain controversial.1Zhao J (2026)Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
Chia Cholesterol Meta-AnalysisFood fortification is a potentially effective approach because it provides necessary micronutrients, but it cannot replicate the nutritional profile and health advantages found in naturally nutrient&#8208;rich foods (Kakkar et&#160;al.&#160;).3Raza Nighat (2026)Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
Chia Cholesterol Meta-AnalysisThe data collected from Asia, China, and Korea show that the increased consumption of fast food leads to obesity and serious health concerns (Wu et&#160;al.&#160;).3Raza Nighat (2026)Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
Chia Cholesterol Meta-Analysis2025 2020 2024 Increased blood levels of LDL can be a risk factor for heart disease, and are frequently linked to saturated fats.3Raza Nighat (2026)Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
Chia Cholesterol Meta-AnalysisACE ALA AR BMI CRP DNA ER GLP&#8208;1 HbA1c HDL IL&#8208;6 LDL LXR MAPK MPO mTOR NADPH NF&#8208;kB NOS PI3K PUFA RNA ROS SCFA TG TNF&#8208;alpha VEGF VLDL 2020 2020 A healthy lifestyle is achieved if the population consumes a diet that is secure, healthy, and dense in nutrients, which can fulfill the needs of the human body for good health and well&#8208;governed physical status.3Raza Nighat (2026)Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claimStudy quality was assessed using the Cochrane Risk of Bias 2 tool and the GRADE framework.
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimCompared with control diets, KD significantly reduced triglycerides (WMD: -22.31 mg/dL; 95% CI: -28.90 to -15.72; p < 0.001; I2 = 69.8%, p < 0.001).
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimHDL-C increased significantly (WMD: 3.52 mg/dL; 95% CI: 1.24 to 5.81; p < 0.001; I2 = 92.5%, p < 0.001).
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimAIMS: The effects of the ketogenic diet (KD) on lipid metabolism remain controversial.
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimFood fortification is a potentially effective approach because it provides necessary micronutrients, but it cannot replicate the nutritional profile and health advantages found in naturally nutrient&#8208;rich foods (Kakkar et&#160;al.&#160;).
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claimThe data collected from Asia, China, and Korea show that the increased consumption of fast food leads to obesity and serious health concerns (Wu et&#160;al.&#160;).
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claim2025 2020 2024 Increased blood levels of LDL can be a risk factor for heart disease, and are frequently linked to saturated fats.
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claimACE ALA AR BMI CRP DNA ER GLP&#8208;1 HbA1c HDL IL&#8208;6 LDL LXR MAPK MPO mTOR NADPH NF&#8208;kB NOS PI3K PUFA RNA ROS SCFA TG TNF&#8208;alpha VEGF VLDL 2020 2020 A healthy lifestyle is achieved if the population consumes a diet that is secure, healthy, and dense in nutrients, which can fulfill the needs of the human body for good health and well&#8208;governed physical status.
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

Source documents

  1. Ketogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
  2. Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights