topicChia Cholesterol Meta-Analysis
claimStudy quality was assessed using the Cochrane Risk of Bias 2 tool and the GRADE framework.
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimCompared with control diets, KD significantly reduced triglycerides (WMD: -22.31 mg/dL; 95% CI: -28.90 to -15.72; p < 0.001; I2 = 69.8%, p < 0.001).
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimHDL-C increased significantly (WMD: 3.52 mg/dL; 95% CI: 1.24 to 5.81; p < 0.001; I2 = 92.5%, p < 0.001).
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimAIMS: The effects of the ketogenic diet (KD) on lipid metabolism remain controversial.
evidence level1
citationZhao J (2026)
sourceKetogenic diet-induced changes in adult lipid metabolism: a comprehensive systematic review and meta-regression of randomized controlled trials.
topicChia Cholesterol Meta-Analysis
claimFood fortification is a potentially effective approach because it provides necessary micronutrients, but it cannot replicate the nutritional profile and health advantages found in naturally nutrient‐rich foods (Kakkar et al. ).
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claimThe data collected from Asia, China, and Korea show that the increased consumption of fast food leads to obesity and serious health concerns (Wu et al. ).
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claim2025 2020 2024 Increased blood levels of LDL can be a risk factor for heart disease, and are frequently linked to saturated fats.
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights
topicChia Cholesterol Meta-Analysis
claimACE ALA AR BMI CRP DNA ER GLP‐1 HbA1c HDL IL‐6 LDL LXR MAPK MPO mTOR NADPH NF‐kB NOS PI3K PUFA RNA ROS SCFA TG TNF‐alpha VEGF VLDL 2020 2020 A healthy lifestyle is achieved if the population consumes a diet that is secure, healthy, and dense in nutrients, which can fulfill the needs of the human body for good health and well‐governed physical status.
evidence level3
citationRaza Nighat (2026)
sourceNutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights