topicChia Blood Pressure Meta-Analysis
claim1 2 Cardiac arrest is associated with high mortality and morbidity, even after successful resuscitation.,While intravascular volume therapy is recognised as a standard component of shock management,its role during and after cardiac arrest remains uncertain.
evidence level1
citationWittig Johannes (2026)
sourceVolume therapy for cardiac arrest: a systematic review and meta-analysis
topicChia Blood Pressure Meta-Analysis
claimThe last systematic review on this topic was conducted by the International Liaison Committee on Resuscitation (ILCOR) in 2010, which concluded that there was insufficient evidence to recommend for or against the routine use of intravenous fluids during cardiac arrest.With new evidence available, an updated systematic review is needed to inform the international guidelines.
evidence level1
citationWittig Johannes (2026)
sourceVolume therapy for cardiac arrest: a systematic review and meta-analysis
topicChia Blood Pressure Meta-Analysis
claimThe aim of this systematic review was to identify, assess, and synthesize the clinical evidence on intra- and post-cardiac arrest volume therapy for adults and children.
evidence level1
citationWittig Johannes (2026)
sourceVolume therapy for cardiac arrest: a systematic review and meta-analysis
topicChia Blood Pressure Meta-Analysis
claim5 6 During cardiac arrest, volume therapy is only recommended in cases when hypovolaemia is evident or suspected.Identifying hypovolaemia during cardiac arrest is challenging, and fluids are sometimes administered empirically during resuscitation.
evidence level1
citationWittig Johannes (2026)
sourceVolume therapy for cardiac arrest: a systematic review and meta-analysis
topicChia Blood Pressure Meta-Analysis
claimModerate evidence indicated that IHG reduced SBP (-5.38 mmHg, 95% CI -6.91 to -3.85; p 2 = 86% and DBP (-2.71 mmHg, 95% CI -3.75 to -1.66; p 2 = 90%), with greater effects observed in hypertensive compared to normotensive groups.
evidence level1
citationLin CW (2026)
sourceThe Optimal Dosage of Isometric Handgrip Exercise for Blood Pressure Reduction: Systematic Review and Meta-Analysis.
topicChia Blood Pressure Meta-Analysis
claimFor meta-regression, lower training intensity protocols ( 3 to 7 days/week) was associated with a diminished effect in SBP (p = 0.032).
evidence level1
citationLin CW (2026)
sourceThe Optimal Dosage of Isometric Handgrip Exercise for Blood Pressure Reduction: Systematic Review and Meta-Analysis.
topicChia Blood Pressure Meta-Analysis
claimIn conclusion, the IHG training significantly lowers SBP and DBP in both normotensive and hypertensive individuals, offering preventive benefits for normotensive individuals at risk for hypertension and therapeutic potential for hypertensive patients.
evidence level1
citationLin CW (2026)
sourceThe Optimal Dosage of Isometric Handgrip Exercise for Blood Pressure Reduction: Systematic Review and Meta-Analysis.
topicChia Blood Pressure Meta-Analysis
claimThe systematic review and meta-analysis aimed to examine the dose-response relationship between isometric handgrip (IHG) training and blood pressure outcomes in normotensive and hypertensive populations.
evidence level1
citationLin CW (2026)
sourceThe Optimal Dosage of Isometric Handgrip Exercise for Blood Pressure Reduction: Systematic Review and Meta-Analysis.