Structured evidence table for Calcium Sleep Quality Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Calcium Sleep Quality Randomized Trial | Recently, pregabalin was found to interact only with the molecular site α2δ‐1, which was also believed as the only relevant functional site of pregabalin. | 2 | Lu Hui (2026) | Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain |
| Calcium Sleep Quality Randomized Trial | [] n n PHN ( = 96) and DPN ( = 204) patients Open‐label, non‐inferiority RCT Flexible, titrated pregabalin Pregabalin effective in DPN (69.1% response); less effective in PHN (46.5%) than lidocaine plaster; both improved allodynia and QoL. | 2 | Lu Hui (2026) | Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain |
| Calcium Sleep Quality Randomized Trial | [] n Diabetic peripheral neuropathy (DPN) patients, = 146 8‐week randomized placebo‐controlled trial Pregabalin 300 mg/day p Significant reductions in pain ( < 0.0001), sleep interference, mood disturbance, and improved QoL compared to placebo. | 2 | Lu Hui (2026) | Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain |
| Calcium Sleep Quality Randomized Trial | 1 1 2 3 3 4 5 6 7 8 9 10 11 1 Pregabalin [(S)‐3‐aminomethyl‐5‐methylhexanoic acid, C₈H₁₇NO₂] is a structural analogue of gamma‐aminobutyric acid (GABA) that exhibits anticonvulsant, analgesic, and anxiolytic properties (Figure ) []. | 2 | Lu Hui (2026) | Consensus on the Clinical Use of Pregabalin in Peripheral Neuropathic Pain |
| Calcium Sleep Quality Randomized Trial | Anxiety and depressive disorders frequently co-occur, and converging evidence from symptom profiles, longitudinal course, shared neurobiological markers, familial aggregation, and treatment response supports a substantial overlap between these conditions []. | 4 | Derkaczew Maria (2026) | Potential Anxiolytic Effects of Selected Inositol Stereoisomers—A Narrative Review |
| Calcium Sleep Quality Randomized Trial | Importantly, even agents considered comparatively “benign”, such as non-benzodiazepine anxiolytics, may rarely cause significant neurological adverse effects in vulnerable individuals, as illustrated by reports of buspirone-associated dyskinesia or dystonia, plausibly related to its interactions with dopaminergic signaling []. | 4 | Derkaczew Maria (2026) | Potential Anxiolytic Effects of Selected Inositol Stereoisomers—A Narrative Review |
| Calcium Sleep Quality Randomized Trial | Recent reports have also raised the possibility that selected cyclitols may exert anxiolytic activity; however, robust clinical evidence remains scarce, and the available data are largely preliminary, often derived from indirect observations or preclinical research []. | 4 | Derkaczew Maria (2026) | Potential Anxiolytic Effects of Selected Inositol Stereoisomers—A Narrative Review |
| Calcium Sleep Quality Randomized Trial | 1 2 3 4 1 Anxiety plays a dual role, encompassing both adaptive and maladaptive dimensions. | 4 | Derkaczew Maria (2026) | Potential Anxiolytic Effects of Selected Inositol Stereoisomers—A Narrative Review |
Source documents