Caffeine Sleep Randomized Trial Evidence Table

Structured evidence table for Caffeine Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Caffeine Sleep Randomized TrialThe 2018 International Olympic Committee (IOC) reported that caffeine is among the five nutritional supplements whose positive effects on athletic performance are supported by scientific evidence [].2Bingol Diedhiou Azize (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
Caffeine Sleep Randomized Trial5 3 6 Caffeine is metabolized by the CYP1A2 enzyme, which is found in the liver and is responsible for approximately 95% of the cytochrome P450 family [].2Bingol Diedhiou Azize (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
Caffeine Sleep Randomized TrialThese metabolic rates are important factors in determining both the level of benefit from the ergogenic effects of caffeine and the risk of exposure to potential side effects in athletes.2Bingol Diedhiou Azize (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
Caffeine Sleep Randomized Trial1 2 3 4 Various nootropic nutritional supplements are preferred by athletes to improve their physical (exercise-related) and cognitive performance.2Bingol Diedhiou Azize (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
Caffeine Sleep Randomized TrialIts production follows the light–dark cycle, resulting in an increased production at night and a decreased production during the day.4Mahdi Nourhène (2026)Melatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
Caffeine Sleep Randomized TrialSupplementation improved both sleep quantity and quality during the subsequent night and enhanced physical performance the following morning, including vertical and horizontal jumps (VJs, HJs) and handgrip strength (HG), and the five-jump test (5-JT) was improved [].4Mahdi Nourhène (2026)Melatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
Caffeine Sleep Randomized Trial9 10 11 12 13 14 15 16 17 18 19 20 Caffeine (1,3,7-trimethylxanthine; CAF) is one of the most globally prevalent psychostimulants worldwide [] and is commonly found in coffee, tea, chocolate, energy drinks, and nutritional supplements such as guarana and kola [].4Mahdi Nourhène (2026)Melatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
Caffeine Sleep Randomized TrialN 1 2 3 4 5 6 7 8 7 Melatonin is a methoxyindole (-acetyl-5-methoxytryptamine; MEL) primarily synthesized from serotonin in the pineal gland [].4Mahdi Nourhène (2026)Melatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
topicCaffeine Sleep Randomized Trial
claimThe 2018 International Olympic Committee (IOC) reported that caffeine is among the five nutritional supplements whose positive effects on athletic performance are supported by scientific evidence [].
evidence level2
citationBingol Diedhiou Azize (2026)
sourceComparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
topicCaffeine Sleep Randomized Trial
claim5 3 6 Caffeine is metabolized by the CYP1A2 enzyme, which is found in the liver and is responsible for approximately 95% of the cytochrome P450 family [].
evidence level2
citationBingol Diedhiou Azize (2026)
sourceComparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
topicCaffeine Sleep Randomized Trial
claimThese metabolic rates are important factors in determining both the level of benefit from the ergogenic effects of caffeine and the risk of exposure to potential side effects in athletes.
evidence level2
citationBingol Diedhiou Azize (2026)
sourceComparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
topicCaffeine Sleep Randomized Trial
claim1 2 3 4 Various nootropic nutritional supplements are preferred by athletes to improve their physical (exercise-related) and cognitive performance.
evidence level2
citationBingol Diedhiou Azize (2026)
sourceComparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
topicCaffeine Sleep Randomized Trial
claimIts production follows the light–dark cycle, resulting in an increased production at night and a decreased production during the day.
evidence level4
citationMahdi Nourhène (2026)
sourceMelatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
topicCaffeine Sleep Randomized Trial
claimSupplementation improved both sleep quantity and quality during the subsequent night and enhanced physical performance the following morning, including vertical and horizontal jumps (VJs, HJs) and handgrip strength (HG), and the five-jump test (5-JT) was improved [].
evidence level4
citationMahdi Nourhène (2026)
sourceMelatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
topicCaffeine Sleep Randomized Trial
claim9 10 11 12 13 14 15 16 17 18 19 20 Caffeine (1,3,7-trimethylxanthine; CAF) is one of the most globally prevalent psychostimulants worldwide [] and is commonly found in coffee, tea, chocolate, energy drinks, and nutritional supplements such as guarana and kola [].
evidence level4
citationMahdi Nourhène (2026)
sourceMelatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study
topicCaffeine Sleep Randomized Trial
claimN 1 2 3 4 5 6 7 8 7 Melatonin is a methoxyindole (-acetyl-5-methoxytryptamine; MEL) primarily synthesized from serotonin in the pineal gland [].
evidence level4
citationMahdi Nourhène (2026)
sourceMelatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study

Source documents

  1. Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study
  2. Melatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study