Caffeine and Sleep Evidence Table

Structured evidence table for Caffeine and Sleep, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Caffeine and SleepResults Compared with the placebo, the combined caffeine + paraxanthine condition was associated with faster 2000-m performance and higher mean power output ( p = 0.044; Cohen's d = 0.30).2Bingol Diedhiou A (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study.
Caffeine and SleepCaffeine alone and paraxanthine alone did not show clear evidence of performance improvement in this sample, although estimates favored both conditions versus placebo.2Bingol Diedhiou A (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study.
Caffeine and SleepConditions containing caffeine were associated with poorer subjective sleep quality, whereas paraxanthine alone showed more favorable sleep-related outcomes.2Bingol Diedhiou A (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study.
Caffeine and SleepBackground Although caffeine is widely used in athletes due to its ergogenic effects, the effects of its main metabolite, paraxanthine, on performance and sleep have not been adequately investigated.2Bingol Diedhiou A (2026)Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study.
Caffeine and Sleep8 9 10 11 Long-term observational studies have repeatedly suggested that habitual coffee and caffeine consumption is associated with a lower risk of clinically diagnosed depression, particularly among women [,].3Turkowska Iwona (2026)Coffee and Caffeine in Depression: Symptom-Level Modulation and Challenges in Nutripsychiatric Interpretation
Caffeine and SleepIn practice, higher coffee intake may co-occur with structured daily routines, occupational engagement and social activity, which are factors that are independently associated with better mental health and are often adjusted for in epidemiological studies [,].3Turkowska Iwona (2026)Coffee and Caffeine in Depression: Symptom-Level Modulation and Challenges in Nutripsychiatric Interpretation
Caffeine and Sleep13 14 15 1 16 17 At the same time, a growing body of evidence indicates that excessive caffeine intake may have unfavourable psychological consequences [].3Turkowska Iwona (2026)Coffee and Caffeine in Depression: Symptom-Level Modulation and Challenges in Nutripsychiatric Interpretation
Caffeine and Sleep1 2 Depression remains one of the leading causes of disability worldwide and continues to represent a major clinical and public health challenge [].3Turkowska Iwona (2026)Coffee and Caffeine in Depression: Symptom-Level Modulation and Challenges in Nutripsychiatric Interpretation

Source documents

  1. Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study.
  2. Coffee and Caffeine in Depression: Symptom-Level Modulation and Challenges in Nutripsychiatric Interpretation