topicCacao Flavanols Blood Pressure Meta-Analysis
claim1 2 3 4 5 Metabolic syndrome (MetS) is characterized by the coexistence of cardiovascular risk factors and metabolic disorders, such as hypertension, insulin resistance, dyslipidemias – elevated triglyceride levels and reduced HDL levels – and increased waist circumference [,].
evidence level1
citationGomes Chagas Amanda (2026)
sourceThe effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis
topicCacao Flavanols Blood Pressure Meta-Analysis
claimThe presence of MetS is a risk factor for other conditions, particularly increasing the risk of developing type 2 diabetes (DM2) by five times and the risk of cardiovascular diseases by three times [].
evidence level1
citationGomes Chagas Amanda (2026)
sourceThe effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis
topicCacao Flavanols Blood Pressure Meta-Analysis
claimIt may be the result from a combination of genetic factors, dietary profile, and physical inactivity [].
evidence level1
citationGomes Chagas Amanda (2026)
sourceThe effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis
topicCacao Flavanols Blood Pressure Meta-Analysis
claimThus, this review aimed to provide an overview of the latest research results on the effects of cacao on the prevention of CVDs and on biomarkers associated with these mechanisms.
evidence level3
citationLee YG (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review.
topicCacao Flavanols Blood Pressure Meta-Analysis
claimCacao, the primary raw material for chocolate and certain beverages, is widely cultivated in the Americas and Asia.
evidence level3
citationLee YG (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review.
topicCacao Flavanols Blood Pressure Meta-Analysis
claimFurthermore, various components of cacao, including phenolic compounds, have been shown to be effective in preventing numerous diseases.
evidence level3
citationLee YG (2026)
sourceCardiovascular Protective Effects and Mechanisms of Action of Cacao: A Comprehensive Review.