topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimWe assessed selection, attrition, performance, detection, attrition, reporting and other biases from low to high risk based on the Cochrane Handbook for Systematic Reviews.
evidence level1
citationJulea M (2025)
sourceThe Effect of Oral Pure Branched-Chain Amino Acid Supplementation on Exercise Performance and Body Composition: A Systematic Review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimOne study found significant differences in body composition after BCAA supplementation.
evidence level1
citationJulea M (2025)
sourceThe Effect of Oral Pure Branched-Chain Amino Acid Supplementation on Exercise Performance and Body Composition: A Systematic Review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimThe results moderately support BCAA reducing muscle soreness; however, there is inconsistent evidence to support BCAAs having an ergogenic effect on strength and endurance.
evidence level1
citationJulea M (2025)
sourceThe Effect of Oral Pure Branched-Chain Amino Acid Supplementation on Exercise Performance and Body Composition: A Systematic Review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimBranched-chain amino acids (BCAAs) are an increasingly popular sports supplement used by athletes as they are advertised to increase endurance, muscle recovery, lean muscle mass, and decrease muscle soreness and fatigue.
evidence level1
citationJulea M (2025)
sourceThe Effect of Oral Pure Branched-Chain Amino Acid Supplementation on Exercise Performance and Body Composition: A Systematic Review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimNext, we integrate evidence on the ergogenic effects of various dietary interventions with existing knowledge on the perception of effort.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimBeta-alanine, caffeine or carbohydrate mouth rinsing are examples of evidence-based ergogenic aids.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimConclusion While current evidence supports a key role for dietary interventions on endurance performance by influencing individuals' perceived effort, more research is needed to determine the optimal doses and precise formulations for different sports, in order to employ a personalized strategy.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimBackground Exercise tolerance is a pivotal factor in determining athletic competitive success, as well as mobility and quality of life in elderly individuals and those afflicted by chronic ailments.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimResults Essential amino acids and leucine showed the most consistent associations with increased MPS and, in older adults, improvements in strength/lean mass.
evidence level4
citationNoh KW (2025)
sourceEffects of Amino Acid Supplementation on Muscle protein metabolism and adaptation: a narrative review of effects on muscle mass, strength, and sex differences.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimConclusion Amino acid supplementation can support muscle anabolism and, in selected contexts, strength and recovery, best viewed as an adjunct to resistance training with individualized dosing/timing.
evidence level4
citationNoh KW (2025)
sourceEffects of Amino Acid Supplementation on Muscle protein metabolism and adaptation: a narrative review of effects on muscle mass, strength, and sex differences.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimPurpose To review the effects of amino acid supplementation including essential, branched-chain, and non-essential amino acids on muscle mass, strength, and adaptation, with a focus on sex-specific differences.
evidence level4
citationNoh KW (2025)
sourceEffects of Amino Acid Supplementation on Muscle protein metabolism and adaptation: a narrative review of effects on muscle mass, strength, and sex differences.
topicBranched Chain Amino Acids Muscle Soreness Randomized Trial
claimMethods PubMed, ScienceDirect, and Google Scholar databases were searched for clinical and nonclinical studies on the effects of supplementation in adults, published between 1990 and 2025.
evidence level4
citationNoh KW (2025)
sourceEffects of Amino Acid Supplementation on Muscle protein metabolism and adaptation: a narrative review of effects on muscle mass, strength, and sex differences.