topicBoswellia Osteoarthritis Meta-Analysis
claimNutritional supplements are increasingly used for KOA due to their low risk, but direct comparative evidence on their efficacy and safety remains scarce.
evidence level1
citationZhang Y (2025)
sourceComparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
topicBoswellia Osteoarthritis Meta-Analysis
claimBackground : Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that can greatly affect quality of life in middle-aged and elderly individuals.
evidence level1
citationZhang Y (2025)
sourceComparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis.
topicBoswellia Osteoarthritis Meta-Analysis
claimBetween 1990 and 2020, OA prevalence increased by over 100%, and the years lived with disability (YLDs) have also risen sharply, creating a substantial economic burden on patients and healthcare systems [].
evidence level3
citationPatel Milan (2026)
sourceNutritional Interventions in Osteoarthritis: Mechanisms, Clinical Evidence, and Translational Opportunities
topicBoswellia Osteoarthritis Meta-Analysis
claimRisk factors such as age, obesity, prior joint injury, and genetics drive this alarming upward trend, especially obesity, as it accounts for a growing fraction of the OA burden worldwide.
evidence level3
citationPatel Milan (2026)
sourceNutritional Interventions in Osteoarthritis: Mechanisms, Clinical Evidence, and Translational Opportunities
topicBoswellia Osteoarthritis Meta-Analysis
claimLong-term use of NSAIDs or corticosteroids carries gastrointestinal and cardiovascular risk and often fails to protect cartilage [].
evidence level3
citationPatel Milan (2026)
sourceNutritional Interventions in Osteoarthritis: Mechanisms, Clinical Evidence, and Translational Opportunities
topicBoswellia Osteoarthritis Meta-Analysis
claim1 1 1 1 Osteoarthritis (OA) affects a growing and expansive portion of the population worldwide.
evidence level3
citationPatel Milan (2026)
sourceNutritional Interventions in Osteoarthritis: Mechanisms, Clinical Evidence, and Translational Opportunities