evidence table

Blueberry Memory Meta-Analysis Evidence Table

Structured evidence table for Blueberry Memory Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Blueberry Memory Meta-AnalysisConclusion The NMA results indicate that in terms of learning and memory functions, raisin and tart cherry ranked higher; in terms of executive functions, the bacopa monnieri compound demonstrated a relatively better intervention effect, providing an important basis for non-drug interventions for cognitive health in the healthy older adults.1Feng X (2026)The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
Blueberry Memory Meta-AnalysisBackground With the accelerating global population aging, age-related cognitive decline has become a significant health concern for the older adults.1Feng X (2026)The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
Blueberry Memory Meta-AnalysisThe limited efficacy and common side effects of pharmacological interventions have made the exploration of safe non-pharmacological strategies an urgent need.1Feng X (2026)The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
Blueberry Memory Meta-AnalysisPolyphenols strengthen the intestinal barrier and reduce endotoxemia; cocoa bean shell extracts protected against oxysterol‐induced intestinal damage and improved gut microbiota composition in preclinical models (Alia et al. ).3Akif Adnan (2026)Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
Blueberry Memory Meta-AnalysisWhile many epidemiological studies correlate polyphenol‐rich diets (e.g., Mediterranean diet) with reduced NCCD risk, causality is uncertain due to confounding and measurement error.3Akif Adnan (2026)Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
Blueberry Memory Meta-AnalysisControlled trials provide more robust evidence but vary widely in doses, formulations, populations and endpoints.3Akif Adnan (2026)Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
Blueberry Memory Meta-AnalysisAMP BBB CNS COMT COSMOS CRP (hs‐CRP) CSF EGCG ENB‐2 (ENB) ENS EVOO FMD GAD‐7 (GAD) GM‐CSF (GM) HDL HOMA‐IR (HOMA) IBS IL IR LDL LPS MCI MMSE NADPH NCCD (NCCDs) PHGG PHQ‐9 (PHQ) PSQI PWV RBANS RCT SCFA SD TNF (TNF‐α) 2024 Non‐communicable chronic diseases account for the majority of morbidity and mortality worldwide.3Akif Adnan (2026)Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
topicBlueberry Memory Meta-Analysis
claimConclusion The NMA results indicate that in terms of learning and memory functions, raisin and tart cherry ranked higher; in terms of executive functions, the bacopa monnieri compound demonstrated a relatively better intervention effect, providing an important basis for non-drug interventions for cognitive health in the healthy older adults.
evidence level1
citationFeng X (2026)
sourceThe effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
topicBlueberry Memory Meta-Analysis
claimBackground With the accelerating global population aging, age-related cognitive decline has become a significant health concern for the older adults.
evidence level1
citationFeng X (2026)
sourceThe effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
topicBlueberry Memory Meta-Analysis
claimThe limited efficacy and common side effects of pharmacological interventions have made the exploration of safe non-pharmacological strategies an urgent need.
evidence level1
citationFeng X (2026)
sourceThe effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
topicBlueberry Memory Meta-Analysis
claimPolyphenols strengthen the intestinal barrier and reduce endotoxemia; cocoa bean shell extracts protected against oxysterol‐induced intestinal damage and improved gut microbiota composition in preclinical models (Alia et al. ).
evidence level3
citationAkif Adnan (2026)
sourceDietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
topicBlueberry Memory Meta-Analysis
claimWhile many epidemiological studies correlate polyphenol‐rich diets (e.g., Mediterranean diet) with reduced NCCD risk, causality is uncertain due to confounding and measurement error.
evidence level3
citationAkif Adnan (2026)
sourceDietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
topicBlueberry Memory Meta-Analysis
claimControlled trials provide more robust evidence but vary widely in doses, formulations, populations and endpoints.
evidence level3
citationAkif Adnan (2026)
sourceDietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
topicBlueberry Memory Meta-Analysis
claimAMP BBB CNS COMT COSMOS CRP (hs‐CRP) CSF EGCG ENB‐2 (ENB) ENS EVOO FMD GAD‐7 (GAD) GM‐CSF (GM) HDL HOMA‐IR (HOMA) IBS IL IR LDL LPS MCI MMSE NADPH NCCD (NCCDs) PHGG PHQ‐9 (PHQ) PSQI PWV RBANS RCT SCFA SD TNF (TNF‐α) 2024 Non‐communicable chronic diseases account for the majority of morbidity and mortality worldwide.
evidence level3
citationAkif Adnan (2026)
sourceDietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities

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Source documents

  1. The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
  2. Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities