topicBlack Seed Oil Mood Randomized Trial
claimNon-pharmacological complementary and alternative medicine (CAM) approaches are widely used in KOA care, but randomized controlled trial (RCT) evidence is distributed across diverse intervention types, settings, comparators, and outcome measures.
evidence level2
citationKang Y (2026)
sourceNon-Pharmacological Complementary and Alternative Therapies for Knee Osteoarthritis: A Scoping Review of Randomized Controlled Trials.
topicBlack Seed Oil Mood Randomized Trial
claimMethods Following the Arksey and O'Malley scoping review framework and the PRISMA-ScR reporting guideline, we searched PubMed, Web of Science, Embase, and the Cochrane Library for RCTs published from 1 January 2016 to 10 January 2026.
evidence level2
citationKang Y (2026)
sourceNon-Pharmacological Complementary and Alternative Therapies for Knee Osteoarthritis: A Scoping Review of Randomized Controlled Trials.
topicBlack Seed Oil Mood Randomized Trial
claimEvidence was summarized descriptively and narratively; no pooled treatment-effect estimates were calculated.
evidence level2
citationKang Y (2026)
sourceNon-Pharmacological Complementary and Alternative Therapies for Knee Osteoarthritis: A Scoping Review of Randomized Controlled Trials.
topicBlack Seed Oil Mood Randomized Trial
claimBackground Knee osteoarthritis (KOA) is a prevalent chronic degenerative joint disorder and a major contributor to pain, disability, and impaired quality of life.
evidence level2
citationKang Y (2026)
sourceNon-Pharmacological Complementary and Alternative Therapies for Knee Osteoarthritis: A Scoping Review of Randomized Controlled Trials.
topicBlack Seed Oil Mood Randomized Trial
claimNigella sativa (black cumin seed) has traditionally been valued for its medicinal properties.
evidence level4
citationAhmed S (2025)
sourceBlack Cumin Seed (<i>Nigella sativa</i>) Confers Anti-Adipogenic Effects in 3T3-L1 Cellular Model and Lipid-Lowering Properties in Human Subjects.
topicBlack Seed Oil Mood Randomized Trial
claimThis study explored its potential in addressing obesity-related conditions by assessing its anti-adipogenic and lipid-lowering effects.
evidence level4
citationAhmed S (2025)
sourceBlack Cumin Seed (<i>Nigella sativa</i>) Confers Anti-Adipogenic Effects in 3T3-L1 Cellular Model and Lipid-Lowering Properties in Human Subjects.