topicBilberry Eye Fatigue Meta-Analysis
claimThis systematic review aimed to evaluate randomized controlled trial (RCT) evidence on the effects of carotenoids, anthocyanins, polyunsaturated fatty acids, and combined nutraceutical formulations on refractive outcomes, axial length, macular pigment optical density (MPOD), visual function, and symptoms of visual fatigue.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicBilberry Eye Fatigue Meta-Analysis
claimEligible studies were RCTs involving individuals with myopia or at risk of myopia, comparing nutritional supplementation with placebo or active controls.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicBilberry Eye Fatigue Meta-Analysis
claimTwo reviewers independently screened studies, extracted data, and assessed risk of bias using the Cochrane RoB 2 tool.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicBilberry Eye Fatigue Meta-Analysis
claimBackground/objectives Nutritional supplementation has been proposed as a potential adjunct strategy in myopia prevention and control through antioxidative, anti-inflammatory, and extracellular matrix-regulating mechanisms.
evidence level1
citationMartinez-Perez C (2025)
sourceNutritional Supplementation for Myopia Prevention and Control: A Systematic Review of Randomized Controlled Trials.
topicBilberry Eye Fatigue Meta-Analysis
claimThey are used to meet daily nutrient requirements, support physiological functions, and address increased nutritional needs, including in special populations.
evidence level4
citationNawathe V (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation.
topicBilberry Eye Fatigue Meta-Analysis
claimIt also highlights evidence in special populations such as pregnant and lactating women, infants, children, adolescents, older adults, and athletes.
evidence level4
citationNawathe V (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation.
topicBilberry Eye Fatigue Meta-Analysis
claimFurthermore, evidence related to nutraceuticals such as omega-3 fatty acids, lutein, curcumin, ginseng, brahmi, ashwagandha, and coenzyme Q10 is included.
evidence level4
citationNawathe V (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation.
topicBilberry Eye Fatigue Meta-Analysis
claimMultivitamin and mineral (MVM) supplements are dietary products that contain a combination of essential vitamins and minerals, and sometimes additional bioactive compounds.
evidence level4
citationNawathe V (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation.