topicBetaine Performance Meta-Analysis
claimOn the other hand, evolving consumer preferences are driving an escalating demand for premium pork, characterized by a high lean yield and reduced fat deposition [].
evidence level1
citationLiu Guanzu (2026)
sourceEffects of Dietary Betaine on Growth Performance, Serum Metabolites, and Meat Quality of Pigs: A Meta-Analysis
topicBetaine Performance Meta-Analysis
claim[] observed that dietary supplementation with 0.1% betaine linearly improved both the average daily gain (ADG) and feed conversion ratio (FCR).
evidence level1
citationLiu Guanzu (2026)
sourceEffects of Dietary Betaine on Growth Performance, Serum Metabolites, and Meat Quality of Pigs: A Meta-Analysis
topicBetaine Performance Meta-Analysis
claimThe existing evidence suggests that the efficacy of betaine is modulated by multiple factors, including the supplement dose, genetic background, basal dietary composition, and growth phase.
evidence level1
citationLiu Guanzu (2026)
sourceEffects of Dietary Betaine on Growth Performance, Serum Metabolites, and Meat Quality of Pigs: A Meta-Analysis
topicBetaine Performance Meta-Analysis
claim1 2 3 Driven by the global shift toward antibiotic-use reduction and sustainable husbandry practices, the investigation into novel feed additives that enhance growth, mitigate stress, and improve meat quality has become a focal point of contemporary research [].
evidence level1
citationLiu Guanzu (2026)
sourceEffects of Dietary Betaine on Growth Performance, Serum Metabolites, and Meat Quality of Pigs: A Meta-Analysis
topicBetaine Performance Meta-Analysis
claimHowever, current evidence is derived primarily from cellular and animal models, providing insights into betaine-mediated metabolic regulation and cytoprotective effects rather than established clinical efficacy.
evidence level3
citationLiu Yinuo (2026)
sourceExploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations
topicBetaine Performance Meta-Analysis
claimBetaine has been reported to enhance ATG3 stability through the SAM/m6A/YTHDF1 axis, which is associated with reduced stem-like characteristics in experimental models of hepatocellular carcinoma [].
evidence level3
citationLiu Yinuo (2026)
sourceExploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations
topicBetaine Performance Meta-Analysis
claimExperimental evidence also indicates that betaine affects hepatic antioxidant defenses and mitochondrial function, both of which are closely related to cellular stress responses and hepatocyte integrity [].
evidence level3
citationLiu Yinuo (2026)
sourceExploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations
topicBetaine Performance Meta-Analysis
claimBetaine, a natural quaternary ammonium compound, has emerged as a primary research subject due to its diverse properties, including osmoregulation, methyl transfer capabilities, participation in hydrogen bond networks, and potential for supramolecular assembly.
evidence level3
citationLiu Yinuo (2026)
sourceExploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations
topicBetaine Performance Meta-Analysis
claimCows receiving betaine had lower rectal temperatures (p = 0.02) and respiration rates (p = 0.01), indicating reduced heat stress.
evidence level4
citationAbdelmegeid M (2026)
sourceShort-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows.
topicBetaine Performance Meta-Analysis
claimRuminal concentrations of volatile fatty acids increased (p ≤ 0.05), and the abundance of beneficial microbial species, such as Fibrobacter succinogenes, Butyrivibrio proteoclasticus, and Megasphaera elsdenii, was enhanced (p ≤ 0.05).
evidence level4
citationAbdelmegeid M (2026)
sourceShort-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows.
topicBetaine Performance Meta-Analysis
claimThis short-term study evaluated the effects of dietary betaine supplementation over 4 weeks on feed intake, milk production, nutrient digestibility, blood metabolites, and ruminal microbial communities in heat-stressed Holstein cows.
evidence level4
citationAbdelmegeid M (2026)
sourceShort-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows.
topicBetaine Performance Meta-Analysis
claimThirty lactating cows were randomly divided into a control group and a treatment group supplemented with 80 g/day of natural betaine extract for 4 weeks during summer.
evidence level4
citationAbdelmegeid M (2026)
sourceShort-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows.