Structured evidence table for Betaine Performance Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Betaine Performance Meta-Analysis | However, current evidence is derived primarily from cellular and animal models, providing insights into betaine-mediated metabolic regulation and cytoprotective effects rather than established clinical efficacy. | 3 | Liu Yinuo (2026) | Exploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations |
| Betaine Performance Meta-Analysis | Betaine has been reported to enhance ATG3 stability through the SAM/m6A/YTHDF1 axis, which is associated with reduced stem-like characteristics in experimental models of hepatocellular carcinoma []. | 3 | Liu Yinuo (2026) | Exploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations |
| Betaine Performance Meta-Analysis | Experimental evidence also indicates that betaine affects hepatic antioxidant defenses and mitochondrial function, both of which are closely related to cellular stress responses and hepatocyte integrity []. | 3 | Liu Yinuo (2026) | Exploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations |
| Betaine Performance Meta-Analysis | Betaine, a natural quaternary ammonium compound, has emerged as a primary research subject due to its diverse properties, including osmoregulation, methyl transfer capabilities, participation in hydrogen bond networks, and potential for supramolecular assembly. | 3 | Liu Yinuo (2026) | Exploring the Multifunctional Roles of Betaine: Traditional Applications, Emerging Technologies, and Green Chemistry Innovations |
| Betaine Performance Meta-Analysis | Cows receiving betaine had lower rectal temperatures (p = 0.02) and respiration rates (p = 0.01), indicating reduced heat stress. | 4 | Abdelmegeid M (2026) | Short-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows. |
| Betaine Performance Meta-Analysis | Ruminal concentrations of volatile fatty acids increased (p ≤ 0.05), and the abundance of beneficial microbial species, such as Fibrobacter succinogenes, Butyrivibrio proteoclasticus, and Megasphaera elsdenii, was enhanced (p ≤ 0.05). | 4 | Abdelmegeid M (2026) | Short-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows. |
| Betaine Performance Meta-Analysis | This short-term study evaluated the effects of dietary betaine supplementation over 4 weeks on feed intake, milk production, nutrient digestibility, blood metabolites, and ruminal microbial communities in heat-stressed Holstein cows. | 4 | Abdelmegeid M (2026) | Short-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows. |
| Betaine Performance Meta-Analysis | Thirty lactating cows were randomly divided into a control group and a treatment group supplemented with 80 g/day of natural betaine extract for 4 weeks during summer. | 4 | Abdelmegeid M (2026) | Short-Term Impact of Betaine Supplementation on Ruminal Microbial Relative Abundance, Nutrient Digestibility, Serum Metabolites, and Milk Composition in Heat-Stressed Dairy Cows. |
Source documents