topicBetaine Exercise Performance Meta-Analysis
claimWhile BFR reduces mechanical stress on joints, the associated metabolic stress and discomfort may limit training performance.
evidence level1
citationZhao B (2026)
sourceCombined effects of blood flow restriction training and nutritional intervention on muscle adaptations: a systematic review and meta-analysis.
topicBetaine Exercise Performance Meta-Analysis
claimCertain nutritional supplements may enhance BFR training effects, but the existing evidence remains inconclusive.
evidence level1
citationZhao B (2026)
sourceCombined effects of blood flow restriction training and nutritional intervention on muscle adaptations: a systematic review and meta-analysis.
topicBetaine Exercise Performance Meta-Analysis
claimNutritional interventions were associated with improvements in muscular endurance (SMD = 0.90; 95% CI: 0.55, 1.25; p Conclusion Current evidence suggests that nutritional interventions may support fatigue resistance and enhance muscular endurance under BFR training conditions, but do not provide a clear additional benefit for maximal strength or hypertrophy.
evidence level1
citationZhao B (2026)
sourceCombined effects of blood flow restriction training and nutritional intervention on muscle adaptations: a systematic review and meta-analysis.
topicBetaine Exercise Performance Meta-Analysis
claimBackground Blood flow restriction (BFR) training induces muscle hypertrophy and strength gains under low-load conditions by restricting blood flow.
evidence level1
citationZhao B (2026)
sourceCombined effects of blood flow restriction training and nutritional intervention on muscle adaptations: a systematic review and meta-analysis.
topicBetaine Exercise Performance Meta-Analysis
claimThe review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), and study quality was assessed using the Cochrane Risk of Bias Tool.
evidence level1
citationPerreras MSL (2025)
sourceEffects of betaine supplementation on endurance exercise performance: a systematic review.
topicBetaine Exercise Performance Meta-Analysis
claimOf these, two studies demonstrated a significant interaction effect on maximum oxygen consumption and mean power at the latter stage of the Wingate Anaerobic Test, two reported a main effect of treatment on mean power, peak power, and oxygen consumption, and one found significant differences in oxygen consumption and blood lactate levels.
evidence level1
citationPerreras MSL (2025)
sourceEffects of betaine supplementation on endurance exercise performance: a systematic review.
topicBetaine Exercise Performance Meta-Analysis
claimConclusion These findings highlight the paucity of evidence regarding the ergogenic potential of betaine in endurance exercise performance and underscore the need for additional, more rigorous research to determine its effectiveness.
evidence level1
citationPerreras MSL (2025)
sourceEffects of betaine supplementation on endurance exercise performance: a systematic review.
topicBetaine Exercise Performance Meta-Analysis
claimPurpose Betaine has been studied for its potential ergogenic effects on strength, power, and body composition.
evidence level1
citationPerreras MSL (2025)
sourceEffects of betaine supplementation on endurance exercise performance: a systematic review.