topicBeta-Glucan LDL Cholesterol Meta-Analysis
claimMany in vitro studies have shown that high concentrations of free fatty acids (FFAs) have a deleterious effect on pancreatic β-cells; in addition, in vivo infusion of FFA in humans and rodents has been found to suppress insulin secretion [].
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta-Glucan LDL Cholesterol Meta-Analysis
claimStudies have shown increased expression of PDX-1 in type 2 diabetes (T2D), allowing its use to evaluate residual pancreatic function [].
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta-Glucan LDL Cholesterol Meta-Analysis
claimChi-square test and/or Fisher’s exact test were used for comparison between qualitative data when the expected count in any cell was found to be less than 5.
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta-Glucan LDL Cholesterol Meta-Analysis
claim1 Attaining optimal glycemic control is a cornerstone in type 1 diabetes (T1D) management, aiming at enhancing the quality of life and minimizing short- and long-term diabetes complications.
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta-Glucan LDL Cholesterol Meta-Analysis
claimFunctional prediction analysis specifically linked this microbial shift to the modulation of Akkermansia -associated metabolic pathways, which subsequently facilitated the activation of host metabolic networks to combat lipid deposition and systemic metabolic stress.
evidence level4
citationGuo Z (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity.
topicBeta-Glucan LDL Cholesterol Meta-Analysis
claimBackground/objectives Although plant-derived dietary fiber and protein are favorable factors for improving host metabolic disorders, it remains unclear whether these two macronutrients exhibit synergistic health benefits.
evidence level4
citationGuo Z (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity.
topicBeta-Glucan LDL Cholesterol Meta-Analysis
claimMethods To address this gap, utilizing oat dietary fiber (GLU) and soybean protein (SBP) as representative bioactive models, we investigated the effects of 5% GLU, 20% SBP, and their combined supplementation on high-fat diet (HFD)-induced metabolic dysregulation in C57BL/6J mice.
evidence level4
citationGuo Z (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity.