topicBeta Glucan Immune Support Meta-Analysis
claimThe activating epigenetic marks prime the expression of immune-related genes and are a direct driving force behind the increased cytokine production after secondary stimulation of trained monocytes and macrophages.
evidence level4
citationJarit-Cabanillas A (2026)
sourceMetabolic support of trained immune responses in myeloid cells.
topicBeta Glucan Immune Support Meta-Analysis
claimTrained immunity (TI) is defined as a form of innate immune memory characterised by a long-lasting ability to develop enhanced responses to a secondary challenge, whether of the same or a different nature than the initial stimulus.
evidence level4
citationJarit-Cabanillas A (2026)
sourceMetabolic support of trained immune responses in myeloid cells.
topicBeta Glucan Immune Support Meta-Analysis
claimThis process is mediated by several established hallmarks, most prominently the existence of activating epigenetic marks and metabolic adaptations.
evidence level4
citationJarit-Cabanillas A (2026)
sourceMetabolic support of trained immune responses in myeloid cells.
topicBeta Glucan Immune Support Meta-Analysis
claimCould β-glucans enhance the immune response to SARS-CoV-2 vaccine by inducing trained immunity and boosting neutralizing antibody production?
evidence level4
citationGolim M (2026)
sourceCould β-glucans enhance the immune response to SARS-CoV-2 vaccine by inducing trained immunity and boosting neutralizing antibody production?