topicBeta Glucan Immune Function Meta-Analysis
claimNevertheless, some memory traits are found in organisms devoid of an adaptive immune system.
evidence level4
citationJarit-Cabanillas Aitor (2026)
sourceMetabolic support of trained immune responses in myeloid cells
topicBeta Glucan Immune Function Meta-Analysis
claimAmong these, microbe-associated molecular patterns, such as β-glucans from the yeast cell wall (), bacterial flagellin (), and muramyl dipeptide (), induce a trained phenotype in myeloid cells.
evidence level4
citationJarit-Cabanillas Aitor (2026)
sourceMetabolic support of trained immune responses in myeloid cells
topicBeta Glucan Immune Function Meta-Analysis
claimNevertheless, the epigenetic changes are not completely fixed within the first hours after the primary stimulation (), and changes in metabolism, such as increased glycolysis and production of intermediates like lactate, acetyl-CoA, and fumarate, can influence the activity of epigenetic enzymes (e.g.
evidence level4
citationJarit-Cabanillas Aitor (2026)
sourceMetabolic support of trained immune responses in myeloid cells
topicBeta Glucan Immune Function Meta-Analysis
claimInvertebrates, including earthworms, cockroaches, and corals, showed a form of innate immunological memory, exhibiting protection against reinfection, or accelerated rejection response upon subsequent exposure to the same foreign tissue in graft models (;;).
evidence level4
citationJarit-Cabanillas Aitor (2026)
sourceMetabolic support of trained immune responses in myeloid cells
topicBeta Glucan Immune Function Meta-Analysis
claimFunctional prediction analysis specifically linked this microbial shift to the modulation of Akkermansia -associated metabolic pathways, which subsequently facilitated the activation of host metabolic networks to combat lipid deposition and systemic metabolic stress.
evidence level4
citationGuo Z (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity.
topicBeta Glucan Immune Function Meta-Analysis
claimBackground/objectives Although plant-derived dietary fiber and protein are favorable factors for improving host metabolic disorders, it remains unclear whether these two macronutrients exhibit synergistic health benefits.
evidence level4
citationGuo Z (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity.
topicBeta Glucan Immune Function Meta-Analysis
claimMethods To address this gap, utilizing oat dietary fiber (GLU) and soybean protein (SBP) as representative bioactive models, we investigated the effects of 5% GLU, 20% SBP, and their combined supplementation on high-fat diet (HFD)-induced metabolic dysregulation in C57BL/6J mice.
evidence level4
citationGuo Z (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity.