topicBeta Glucan Cholesterol Meta-Analysis
claimMany in vitro studies have shown that high concentrations of free fatty acids (FFAs) have a deleterious effect on pancreatic β-cells; in addition, in vivo infusion of FFA in humans and rodents has been found to suppress insulin secretion [].
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta Glucan Cholesterol Meta-Analysis
claimStudies have shown increased expression of PDX-1 in type 2 diabetes (T2D), allowing its use to evaluate residual pancreatic function [].
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta Glucan Cholesterol Meta-Analysis
claimChi-square test and/or Fisher’s exact test were used for comparison between qualitative data when the expected count in any cell was found to be less than 5.
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta Glucan Cholesterol Meta-Analysis
claim1 Attaining optimal glycemic control is a cornerstone in type 1 diabetes (T1D) management, aiming at enhancing the quality of life and minimizing short- and long-term diabetes complications.
evidence level2
citationAfify Mohamed Abu El Asrar (2026)
sourceEffect of Oat Flakes on Glycemic Variability, Dyslipidemia, and Pancreatic Duodenum Homeobox-1 (PDX-1) Level Among Adolescents with Type 1 Diabetes: A Randomized Crossover Study
topicBeta Glucan Cholesterol Meta-Analysis
claim1 2 3 4 5 6 7 8 9 10 11 Obesity has emerged as a major global public health challenge and is closely associated with a range of metabolic complications, including dyslipidemia, insulin resistance and metabolic dysfunction-associated fatty liver disease (MAFLD) [,,,].
evidence level4
citationGuo Zongzhen (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity
topicBeta Glucan Cholesterol Meta-Analysis
claimConsistent with these regulatory effects, higher intake of whole grain has been shown to improve long-term weight management and reduce cardiometabolic risk profiles, as supported by rigorous prospective cohort studies and systematic evaluations of dietary patterns [,,].
evidence level4
citationGuo Zongzhen (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity
topicBeta Glucan Cholesterol Meta-Analysis
claimMechanistic studies in high-fat diet (HFD)-fed mice also indicate that β-glucan may ameliorate insulin resistance and intestinal barrier dysfunction, providing a plausible link to improved glucose homeostasis [].
evidence level4
citationGuo Zongzhen (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity
topicBeta Glucan Cholesterol Meta-Analysis
claimAlthough pharmacological and surgical interventions offer clinical benefits for specific populations with obesity, scalable and sustainable population-level prevention largely depends on dietary strategies that enhance metabolic health.
evidence level4
citationGuo Zongzhen (2026)
sourceCombined Oat β-Glucan and Soy Protein Isolate Reprogram Gut Microbiota and Improve Metabolic Dysfunction in Diet-Induced Obesity