topicBeta Alanine Exercise Performance Meta-Analysis
claimMethodological quality was assessed using the Cochrane RoB 2.0 tool, and the certainty of evidence was evaluated via the GRADE framework.
evidence level1
citationLiang W (2026)
sourceNo ergogeniceffect of β-alanine on repeated sprint ability: a systematic review and multilevel meta-analysis of randomized controlled trials.
topicBeta Alanine Exercise Performance Meta-Analysis
claimConclusion In conclusion, chronic β-alanine supplementation does not provide a clear improvement in total work capacity, maximal anaerobic power, or fatigue resistance during repeated sprinting.
evidence level1
citationLiang W (2026)
sourceNo ergogeniceffect of β-alanine on repeated sprint ability: a systematic review and multilevel meta-analysis of randomized controlled trials.
topicBeta Alanine Exercise Performance Meta-Analysis
claimObjective Chronic beta-alanine supplementation is a prevalent nutritional strategy to augment intracellular buffering capacity via elevated muscle carnosine.
evidence level1
citationLiang W (2026)
sourceNo ergogeniceffect of β-alanine on repeated sprint ability: a systematic review and multilevel meta-analysis of randomized controlled trials.
topicBeta Alanine Exercise Performance Meta-Analysis
claimWhile its ergogenic efficacy in continuous, high-intensity exercise is established, its impact on repeated sprint ability (RSA)-governed by extremely brief work bouts and phosphocreatine (PCr) kinetics-remains equivocal.
evidence level1
citationLiang W (2026)
sourceNo ergogeniceffect of β-alanine on repeated sprint ability: a systematic review and multilevel meta-analysis of randomized controlled trials.
topicBeta Alanine Exercise Performance Meta-Analysis
claimAlthough generally considered safe, their combined use with high-intensity training may increase the risk of exertional rhabdomyolysis and secondary liver or kidney injury.
evidence level4
citationChowaniec P (2026)
sourceExercise-Induced Rhabdomyolysis With Supplements (Creatine, β-Alanine, Citrulline Malate, and β-Ecdysterone).
topicBeta Alanine Exercise Performance Meta-Analysis
claimLaboratory evaluation revealed markedly elevated creatine kinase (>120,000 U/L) and increased aminotransferases (aspartate aminotransferase (AST) 1,275 U/L; alanine aminotransferase (ALT) 337 U/L), with preserved renal function (creatinine 1.0 mg/dL; estimated glomerular filtration rate (eGFR) 108 mL/min/1.73 m²).
evidence level4
citationChowaniec P (2026)
sourceExercise-Induced Rhabdomyolysis With Supplements (Creatine, β-Alanine, Citrulline Malate, and β-Ecdysterone).
topicBeta Alanine Exercise Performance Meta-Analysis
claimCreatine and β-alanine enhance exercise capacity through complementary mechanisms involving adenosine triphosphate (ATP) resynthesis and intracellular buffering, potentially enabling greater training loads and increasing risk of muscle injury.
evidence level4
citationChowaniec P (2026)
sourceExercise-Induced Rhabdomyolysis With Supplements (Creatine, β-Alanine, Citrulline Malate, and β-Ecdysterone).
topicBeta Alanine Exercise Performance Meta-Analysis
claimDietary supplements such as creatine, β-alanine, citrulline malate (CM), phosphatidic acid (PA), and β-ecdysterone are widely used to enhance exercise performance and muscle hypertrophy.
evidence level4
citationChowaniec P (2026)
sourceExercise-Induced Rhabdomyolysis With Supplements (Creatine, β-Alanine, Citrulline Malate, and β-Ecdysterone).