Structured evidence table for Berberine Liver Enzymes Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Berberine Liver Enzymes Meta-Analysis | Prediabetes is defined as an intermediate metabolic state characterized by impaired fasting glucose and/or impaired glucose tolerance, associated with a high risk of progression to diabetes and vascular dysfunction [,]. | 1 | Muacevic Alexander (2026) | A Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations |
| Berberine Liver Enzymes Meta-Analysis | However, long-term use of conventional antidiabetic agents has been associated with adverse effects, reduced tolerance, and diminished efficacy in certain populations [,]. | 1 | Muacevic Alexander (2026) | A Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations |
| Berberine Liver Enzymes Meta-Analysis | 12 13 14 15 16 17 18 Aloe vera Evidence from both clinical studies (involving human participants) and preclinical studies (including in vivo and in vitro experimental models) indicates that several herbal medicines exhibit antihyperglycaemic effects through multiple biological mechanisms [,]. | 1 | Muacevic Alexander (2026) | A Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations |
| Berberine Liver Enzymes Meta-Analysis | 1 2 3 4 5 6 7 8 9 8 10 11 Diabetes mellitus is a persistent metabolic condition characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both []. | 1 | Muacevic Alexander (2026) | A Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations |
| Berberine Liver Enzymes Meta-Analysis | The occurrence and development of metabolic dysfunction-associated steatotic liver disease (MASLD) are closely related to intestinal flora imbalance, intestinal barrier damage, and gut-liver axis dysfunction. | 4 | Deng H (2026) | TCM-Derived Natural Compounds Targeting the Gut Microbiota in Metabolic Dysfunction-Associated Steatotic Liver Disease: Gut-Liver Axis Mechanisms, Safety Considerations, and Translational Challenges. |
| Berberine Liver Enzymes Meta-Analysis | Existing evidence indicates that Chinese herbal monomers have a three-in-one intervention advantage of microecological remodeling-metabolic regulation-inflammation inhibition, but their long-term medication safety, toxic target organs, dose-effect/toxicity relationships, and potential drug interactions still need further clarification. | 4 | Deng H (2026) | TCM-Derived Natural Compounds Targeting the Gut Microbiota in Metabolic Dysfunction-Associated Steatotic Liver Disease: Gut-Liver Axis Mechanisms, Safety Considerations, and Translational Challenges. |
| Berberine Liver Enzymes Meta-Analysis | Due to their multi-target regulatory effects and advantages in intestinal microecological intervention, Chinese herbal monomers have shown promising application prospects in the prevention and treatment of MASLD. | 4 | Deng H (2026) | TCM-Derived Natural Compounds Targeting the Gut Microbiota in Metabolic Dysfunction-Associated Steatotic Liver Disease: Gut-Liver Axis Mechanisms, Safety Considerations, and Translational Challenges. |
Source documents