topicAvocado Cholesterol Meta-Analysis
claimAlthough with a lesser degree of evidence than established dementia risk factors such as low education, visual impairment, diabetes, hypertension or social isolation, evidence is accumulating on the relationship between dietary factors and cognitive functioning [].
evidence level2
citationRos Emilio (2026)
sourceAre avocados good for the brain? Most likely yes, in spite of their lack of effect on cognitive performance in a well-conducted 6-month randomized controlled trial
topicAvocado Cholesterol Meta-Analysis
claimCohort studies suggest that consumption of healthy foods and adherence to plant-based dietary patterns, such as the Mediterranean diet, are associated with reduced risk of cognitive disorders [,,].
evidence level2
citationRos Emilio (2026)
sourceAre avocados good for the brain? Most likely yes, in spite of their lack of effect on cognitive performance in a well-conducted 6-month randomized controlled trial
topicAvocado Cholesterol Meta-Analysis
claimMediterranean-type dietary patterns are reputed as both heart-healthy and environmentally sustainable []; additionally, evidence from prospective studies suggest a favorable association with cognitive decline, but no clear link with all-cause dementia or Alzheimer’s disease, the most frequent cause of dementia [,,].
evidence level2
citationRos Emilio (2026)
sourceAre avocados good for the brain? Most likely yes, in spite of their lack of effect on cognitive performance in a well-conducted 6-month randomized controlled trial
topicAvocado Cholesterol Meta-Analysis
claim1 [2] [3] [4] 5 2 3 6 As population ages, cognitive decline and dementia are becoming leading causes of disability worldwide.
evidence level2
citationRos Emilio (2026)
sourceAre avocados good for the brain? Most likely yes, in spite of their lack of effect on cognitive performance in a well-conducted 6-month randomized controlled trial
topicAvocado Cholesterol Meta-Analysis
claimBackground Avocado consumption has been associated with improvements in diet quality and cardiometabolic risk factors, but effects on serum metabolite profiles remain underexplored.
evidence level4
citationMatthan NR (2026)
sourceSerum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.
topicAvocado Cholesterol Meta-Analysis
claimPre-post intervention changes in metabolites, cardiometabolic risk factors (blood pressure, lipid profile, glucose, insulin, high-sensitivity C-reactive protein), visceral adipose tissue volume, and hepatic fat fraction were evaluated using Wilcoxon tests.
evidence level4
citationMatthan NR (2026)
sourceSerum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.
topicAvocado Cholesterol Meta-Analysis
claimConclusions Avocado intake was associated with subtle shifts in serum metabolites related to lipid, carbohydrate, and amino acid metabolism, with weak effects on visceral adipose tissue volume, plasma triglycerides, and total cholesterol concentrations.
evidence level4
citationMatthan NR (2026)
sourceSerum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.
topicAvocado Cholesterol Meta-Analysis
claimMethods Secondary analysis was conducted using untargeted metabolomics to assess fasting serum metabolite profiles at baseline (preintervention) and 6 months (postintervention) in a subset of participants with abdominal obesity from the HAT (Habitual Diet and Avocado Trial), who were randomized to the avocado group (n = 120; 70% women; 49 ± 13 years of age; body mass index 33.1 ± 5.7 kg/m 2 ).
evidence level4
citationMatthan NR (2026)
sourceSerum Metabolite Profiles in Adults With Abdominal Obesity in Response to Consuming 1 Avocado Daily for 6 Months: An Exploratory Analysis.