topicArtichoke Cholesterol Meta-Analysis
claim1 2 3 Obesity is a multifactorial disease defined as abnormal or excessive fat accumulation that presents a risk to health because it is a major risk factor for several noncommunicable diseases (NCDs), such as cardiovascular diseases, diabetes, and several types of cancer [].
evidence level1
citationPujia Carmelo (2026)
sourceEffect of
Citrus bergamia
Supplementation on Body Composition in Humans: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicArtichoke Cholesterol Meta-Analysis
claimFurthermore, obesity and its associated health problems have a significant economic impact on the global healthcare system [,].
evidence level1
citationPujia Carmelo (2026)
sourceEffect of
Citrus bergamia
Supplementation on Body Composition in Humans: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicArtichoke Cholesterol Meta-Analysis
claimIt is well known that a weight loss of between 5% and 10% is sufficient to achieve clinically significant improvements in health risk factors [].
evidence level1
citationPujia Carmelo (2026)
sourceEffect of
Citrus bergamia
Supplementation on Body Composition in Humans: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicArtichoke Cholesterol Meta-Analysis
claimIt is a major public health concern that has reached pandemic proportions worldwide.
evidence level1
citationPujia Carmelo (2026)
sourceEffect of
Citrus bergamia
Supplementation on Body Composition in Humans: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
topicArtichoke Cholesterol Meta-Analysis
claimCardiovascular disease (CVD) remains the leading cause of death worldwide, with elevated low-density lipoprotein cholesterol (LDL-C) as a major risk factor.
evidence level3
citationJacobo-Velázquez DA (2025)
sourceFunctional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index.
topicArtichoke Cholesterol Meta-Analysis
claimBuilding on these strategies, the CLCI is then proposed as a practical scoring system, analogous to the glycemic index for blood sugar, that integrates the evidence-based potency of ingredients, effective dosing, and synergistic interactions into a single metric.
evidence level3
citationJacobo-Velázquez DA (2025)
sourceFunctional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index.
topicArtichoke Cholesterol Meta-Analysis
claimBeyond medications, dietary interventions and functional foods offer significant cholesterol-lowering potential.
evidence level3
citationJacobo-Velázquez DA (2025)
sourceFunctional Foods for Cholesterol Management: A Review of the Mechanisms, Efficacy, and a Novel Cholesterol-Lowering Capacity Index.