topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimPerformance in the back squat was significantly reduced in the placebo-group, but not in the ALA-group.
evidence level4
citationIsenmann E (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimConclusions Our data indicate possible effects of ALA supplementation, during intensive training periods result in a reduction of muscle damage, inflammation and an increase of recovery.
evidence level4
citationIsenmann E (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimBackground Alpha lipoic acid (ALA) has been demonstrated to have anti-inflammatory activity and was tested as a drug for the treatment of various diseases.
evidence level4
citationIsenmann E (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimALA is also frequently used as a nutrition supplement, in healthy individuals or in competitive athletes.
evidence level4
citationIsenmann E (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimALA resulted in significantly increased resting TAC and bilirubin concentrations.
evidence level4
citationGeorgakouli K (2018)
sourceExercise and Redox Status Responses Following Alpha-Lipoic Acid Supplementation in G6PD Deficient Individuals.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimMoreover, TAC increased immediately and 1h after exercise following both treatment periods, whereas bilirubin increased immediately after and 1h after exercise following only ALA.
evidence level4
citationGeorgakouli K (2018)
sourceExercise and Redox Status Responses Following Alpha-Lipoic Acid Supplementation in G6PD Deficient Individuals.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimG6PD deficiency renders cells more susceptible to oxidative insults, while antioxidant dietary supplementation could restore redox balance and ameliorate exercise-induced oxidative stress.
evidence level4
citationGeorgakouli K (2018)
sourceExercise and Redox Status Responses Following Alpha-Lipoic Acid Supplementation in G6PD Deficient Individuals.
topicAlpha Lipoic Acid Oxidative Stress Exercise Randomized Trial
claimTo examine the effects of alpha-lipoic acid (ALA) supplementation on redox status indices in G6PD deficient individuals, eight male adults with G6PD deficiency (D) participated in this randomized double-blind placebo-controlled crossover trial.
evidence level4
citationGeorgakouli K (2018)
sourceExercise and Redox Status Responses Following Alpha-Lipoic Acid Supplementation in G6PD Deficient Individuals.