Does Alpha Lipoic Acid Oxidative Stress Exercise Randomized Trial work?

The current Migaku evidence database contains 2 reusable source documents for Alpha Lipoic Acid Oxidative Stress Exercise Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Performance in the back squat was significantly reduced in the placebo-group, but not in the ALA-group. [Isenmann E (2020); evidence level 4] - Conclusions Our data indicate possible effects of ALA supplementation, during intensive training periods result in a reduction of muscle damage, inflammation and an increase of recovery. [Isenmann E (2020); evidence level 4] - Background Alpha lipoic acid (ALA) has been demonstrated to have anti-inflammatory activity and was tested as a drug for the treatment of various diseases. [Isenmann E (2020); evidence level 4] - ALA is also frequently used as a nutrition supplement, in healthy individuals or in competitive athletes. [Isenmann E (2020); evidence level 4] - ALA resulted in significantly increased resting TAC and bilirubin concentrations. [Georgakouli K (2018); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.