topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimThis systematic review synthesized current evidence regarding the reversal of cardiovascular risk biomarkers after smoking cessation, with emphasis on the timing and magnitude of biomarker normalization.
evidence level1
citationMohammad A (2026)
sourcePhysiologic Recovery After Smoking Cessation: A Systematic Review of Inflammatory and Cardiovascular Biomarker Changes.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimRisk of bias was assessed using the Cochrane Risk of Bias 2 (RoB 2) tool and the Risk of Bias in Nonrandomized Studies-of Interventions (ROBINS-I) instrument, and findings were synthesized narratively because of methodological heterogeneity.
evidence level1
citationMohammad A (2026)
sourcePhysiologic Recovery After Smoking Cessation: A Systematic Review of Inflammatory and Cardiovascular Biomarker Changes.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimOverall, smoking cessation was associated with progressive improvement in multiple cardiovascular risk pathways, supporting its critical role in cardiovascular prevention and highlighting the potential value of biomarker-guided approaches in future risk-reduction strategies.
evidence level1
citationMohammad A (2026)
sourcePhysiologic Recovery After Smoking Cessation: A Systematic Review of Inflammatory and Cardiovascular Biomarker Changes.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimCigarette smoking remains a major modifiable contributor to cardiovascular morbidity and mortality through mechanisms involving systemic inflammation, oxidative stress, endothelial dysfunction, dyslipidemia, and hematologic abnormalities.
evidence level1
citationMohammad A (2026)
sourcePhysiologic Recovery After Smoking Cessation: A Systematic Review of Inflammatory and Cardiovascular Biomarker Changes.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimThis systematic review aimed to synthesize current clinical evidence on dietary supplementation for OS management in young adults undergoing intensive exercise and to evaluate study methodology critically.
evidence level1
citationKakouris V (2026)
sourceDietary Supplements and Oxidative Stress Management in Young Adults Following Intensive Exercise: A Systematic Review.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimThe review was conducted in accordance with PRISMA 2021 guidelines and the Cochrane Risk of Bias (RoB 2.0) framework and was prospectively registered in PROSPERO.
evidence level1
citationKakouris V (2026)
sourceDietary Supplements and Oxidative Stress Management in Young Adults Following Intensive Exercise: A Systematic Review.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimWell-designed, long-term randomized controlled trials are required to establish robust, evidence-based guidelines for dietary supplement use in managing exercise-induced OS in young adults.
evidence level1
citationKakouris V (2026)
sourceDietary Supplements and Oxidative Stress Management in Young Adults Following Intensive Exercise: A Systematic Review.
topicAlpha-Lipoic Acid Exercise Recovery Randomized Trial
claimStrenuous exercise is a well-established physiological stimulus that enhances muscular strength and hypertrophy but can also increase reactive oxygen species production, leading to oxidative stress (OS).
evidence level1
citationKakouris V (2026)
sourceDietary Supplements and Oxidative Stress Management in Young Adults Following Intensive Exercise: A Systematic Review.