topicAlpha Gpc Cognitive Performance Randomized Trial
claimNext, we integrate evidence on the ergogenic effects of various dietary interventions with existing knowledge on the perception of effort.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicAlpha Gpc Cognitive Performance Randomized Trial
claimBeta-alanine, caffeine or carbohydrate mouth rinsing are examples of evidence-based ergogenic aids.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicAlpha Gpc Cognitive Performance Randomized Trial
claimConclusion While current evidence supports a key role for dietary interventions on endurance performance by influencing individuals' perceived effort, more research is needed to determine the optimal doses and precise formulations for different sports, in order to employ a personalized strategy.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicAlpha Gpc Cognitive Performance Randomized Trial
claimBackground Exercise tolerance is a pivotal factor in determining athletic competitive success, as well as mobility and quality of life in elderly individuals and those afflicted by chronic ailments.
evidence level4
citationStrasser B (2026)
sourceDietary interventions interact with the perception of effort and enhance endurance performance: a brief narrative review.
topicAlpha Gpc Cognitive Performance Randomized Trial
claimAlthough L-α-GPC has been discussed in both neurodegenerative and vascular-related cognitive disorders, the available evidence remains heterogeneous.
evidence level4
citationPutri Vannisa Artasya (2026)
sourceL-α-GPC in Cognitive Decline: Mechanisms and Clinical Evidence in Neurodegenerative Disorders
topicAlpha Gpc Cognitive Performance Randomized Trial
claimTherefore, a careful and contextualized interpretation of the literature is necessary, particularly when comparing evidence across Alzheimer’s disease, Parkinson’s disease-related cognitive decline, and cognitive impairment associated with cerebrovascular conditions.
evidence level4
citationPutri Vannisa Artasya (2026)
sourceL-α-GPC in Cognitive Decline: Mechanisms and Clinical Evidence in Neurodegenerative Disorders
topicAlpha Gpc Cognitive Performance Randomized Trial
claimGiven this background, the present narrative review focuses primarily on the mechanistic and clinical evidence regarding L-α-GPC in cognitive decline associated with neurodegenerative disorders, while also acknowledging relevant findings from studies of vascular- or cerebrovascular-related cognitive impairment where appropriate.
evidence level4
citationPutri Vannisa Artasya (2026)
sourceL-α-GPC in Cognitive Decline: Mechanisms and Clinical Evidence in Neurodegenerative Disorders
topicAlpha Gpc Cognitive Performance Randomized Trial
claim1 2 Neurodegeneration involves the progressive loss of neuronal structure and function, leading to cognitive and motor impairments.
evidence level4
citationPutri Vannisa Artasya (2026)
sourceL-α-GPC in Cognitive Decline: Mechanisms and Clinical Evidence in Neurodegenerative Disorders